To better understand the role of immunocompetent hosts in the diffusion of Pneumocystis in the environment, airborne shedding of Pneumocystis carinii in the surrounding air of experimentally infected Sprague Dawley rats was quantified by means of a real-time PCR assay, in parallel with the kinetics of P. carinii loads in lungs and specific serum antibody titres. Pneumocystis-free Sprague Dawley...

Four strains of rats were each infected intrabronchially with approximately 10(8) CFU of Bordetella pertussis 18-323 encased in fine agarose beads. After 8 days, Sprague-Dawley rats developed the highest incidence of coughing paroxysms, as monitored with voice-activated tape recorders; Brown Norway, Lewis, and Hooded Lister rats coughed significantly less frequently. Marked leukocytosis, with c...

Introduction:This study was carried out to investigate the effect of bael(Aegle marmelos) on glucose,cholesterol,triglyceride,creatinine levels and the activity of ALT and AST in the serum of diabetic rats.   Method:45 Adult male sprague dawley rats were selected.the brats were divided into three groups.the first group was considered as negative CONTROL(non-diabetic rats)and diabetes mellitus...

BACKGROUND Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well established for these analytes. Reference intervals as presently defined for these analytes in Sprague-Dawley rats have not used international...

   According to Iran’s folk medicine, camphor, a crystalline ketone obtained from essential oils of Cinnamomum camphora, has both sexual behavior attenuating and enhancing properties. This study examined the effects of camphor on sexual behavior in male rats. Twenty four sexually mature male Sprague-Dawley rats were randomly divided into 4 groups receiving daily i.p. injections of oliv...

Purpose: To investigate the inhibitory effect of strontium ranelate on alveolar bone resorption in diabetic rats with periodontitis, and mechanism involved.Methods: Forty-five Sprague-Dawley (SD) were allocated to 3 groups, viz, control, periodontitis + groups. Diabetes was induced via i.v. administration streptozotocin (STZ) (45 mg/kg). Then, a rat model established by ligating neck upper left...

The role of sodium retention and consequent changes in cerebrospinal fluid sodium concentration in the genesis of hypertension in Dahl rats was evaluated. Dahl salt-sensitive (DS, n = 7), Dahl salt-resistant (DR, n = 7), and Sprague-Dawley (n = 6) rats were housed in metabolic cages and instrumented with a stainless steel cannula in the cisterna magna and a femoral arterial catheter. A blood sa...

objective(s): the present study aims at examining the motor coordination performance, serum and cerebellar estrogen, as well as erβ levels, of ovariectomized rats (as menopausal model) following regular exercise. materials and methods:ten female sprague dawley ratsaged 12 weeks old were randomly divided into two groups; all of which underwent ovariectomy. the first group was treated with regula...

Objective: The aim of this study was to investigate the potentially deleterious effect in vivo high-fructose feeding rats on ex hemodynamic recovery and infarct size isolated rat hearts subjected low-flow ischemia reperfusion.
 Methods: After Sprague-Dawley male with a (n=9), high-glucose (n=9) or standard diet for four weeks, were extirpated perfused Krebs-Henseleit solution 15 min; there...

Continuously performing heavy activities will damage tissues and cells cause oxidative stress. Fortunately, this can be reduced by giving antioxidants to reduce free radicals. This study uses the forced swimming test model determine effect of Javanese ginseng root extract on superoxide dismutase levels in male white Sprague Dawley rats. The samples were 30 rats divided into five groups: negativ...