BACKGROUND Transcutaneous acupoint electrical stimulation (TAES) as a needleless acupuncture has the same effect like traditional manual acupuncture. The combination of TAES and anesthesia has been proved valid in enhancing the anesthetic effects but its mechanisms are still not clear. METHODS In this study, we investigated the effect of TAES on anesthesia with an electroencephalogram (EEG) o...

awake intubation is the choice for airway management in anticipated difficult airway (da), which means establishing airway without induction of deep sedation; however, in cases where sedation is precarious, decision in emergency situations, success in awake intubation is dependent on proper regional airway block. a 21 year old man with bilateral temporo-mandibular ankyolosis and a 25 years old ...

BACKGROUND The default mode network (DMN) is closely associated with the maintenance of alertness and cognitive functions. This study aimed to observe the changes in DMN induced by increasing doses of propofol and progressively deepening sedation. METHODS Twelve healthy subjects were selected; they received target-controlled infusion of propofol (1.0 and 3.0 μg/mL of plasma) and underwent fun...

INTRODUCTION Deep sedation in critically ill patients is associated with a longer duration of mechanical ventilation and a prolonged length of stay in the intensive care unit. Several protocols have been used to improve these outcomes. We implement and evaluate an analgesia-based, goal-directed, nurse-driven sedation protocol used to treat critically ill patients who receive mechanical ventilat...

1911 I 2002, the government of the Netherlands explicitly legalized euthanasia and physician-assisted suicide. These controversial endof-life practices had been openly tolerated and studied for many years before legalization, and Dutch physicians were expected to voluntarily report their participation in these acts, trusting that they would be acquitted of any legal wrongdoing provided that the...

The risk for complications while providing moderate and deep sedation is greatest when caring for patients already medically compromised. It is reassuring that significant untoward events can generally be prevented by careful preoperative assessment, along with attentive intraoperative monitoring and support. Nevertheless, we must be prepared to manage untoward events should they arise. This co...

INRODUCTION Bispectral Index is an objective tool to assess electroencephalographic activity and measure the effect of certain sedatives and hypnotics on the brain. In addition, there are certain subjective tools such as the observer's assessment of alertness and sedation which are used. The correlation between BIS and the concentration of propofol in the brain, and the relationship between the...

BACKGROUND The practice of continuous deep sedation is a challenging clinical intervention with demanding clinical and ethical decision-making. Though current research indicates that healthcare professionals' involvement in such decisions is associated with emotional stress, little is known about sedation-related emotional burden. This study aims to systematically review the evidence on the imp...

AIM To determine the effect of sedation with propofol on adenoma detection rate (ADR) and cecal intubation rates (CIR) in average risk screening colonoscopies compared to moderate sedation. METHODS We conducted a retrospective chart review of 2604 first-time average risk screening colonoscopies performed at MD Anderson Cancer Center from 2010-2013. ADR and CIR were calculated in each sedation...

In 2016, a law came into force in France granting terminally ill patients the right to continuous deep sedation (CDS) until death. This right was proposed as an alternative to euthanasia and presented as the 'French response' to problems at the end of life. The law draws a distinction between CDS and euthanasia and other forms of sympton control at the end of life. France is the first country i...