نتایج جستجو برای: deep stratum
تعداد نتایج: 216320 فیلتر نتایج به سال:
The structural basis of the permeability barrier in mammalian epidermis was examined by tracer and freeze-fracture techniques. Water-soluble tracers (horesradish peroxidase, lanthanum, ferritin) were injected into neonatal mice or into isolated upper epidermal sheets obtained with staphylococcal exfoliatin. Tracers percolated through the intercellular spaces to the upper stratum granulosum, whe...
The bundle structure of the space A of Ashtekar’s generalized connections is investigated in the compact case. It is proven that every stratum is a locally trivial fibre bundle. The only stratum being a principal fibre bundle is the generic stratum. Its structure group equals the space G of all generalized gauge transforms modulo the constant center-valued gauge transforms. For abelian gauge th...
The temperature distribution in human body regulates variety of biological mechanism. Human Skin is a very complex structure and abnormality in temperature of various layer of skin play important role for curing and treatment diseases like tumor, cancer etc. The eight layers of human skin namely stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum germinativum, papill...
PURPOSE To determine the response rate to oral capsular fenretinide in children with recurrent or biopsy proven refractory high-risk neuroblastoma. EXPERIMENTAL DESIGN Patients received 7 days of fenretinide: 2,475 mg/m(2)/d divided TID (<18 years) or 1,800 mg/m(2)/d divided BID (≥18 years) every 21 days for a maximum of 30 courses. Patients with stable or responding disease after course 30 c...
In order to explain the apparent losses of rain ascribable to seeding at the Whitetop trial, particularly large and highly significant in the stratum E (but not in the opposite stratum W) of experimental days, it has been hypothesized that seeding causes widespread cloudiness and subsequent lowering of ground temperatures. This hypothesis is flatly contradicted by the observations: the seeded E...
The problem of organizing the temporal behavior of digital systems is discussed. This problem is mainly associated with providing the interface between physical (natural) and logical (artificial) time. The most common method of interfacing is based on a system clock that removes physical time from the behavior models A number of algorithms that can be easily formulated in logical time present a...
BACKGROUND Painless, rapid, controlled, minimally invasive molecular transport across human skin for drug delivery and analyte acquisition is of widespread interest. Creation of microconduits through the stratum corneum and epidermis is achieved by stochastic scissioning events localized to typically 250 microm diameter areas of human skin in vivo. METHODS Microscissioning is achieved by a li...
BACKGROUND Treatment options are scarce in pretreated advanced non-small-cell lung cancer (NSCLC) patients. RAD001, an oral inhibitor of the mammalian target of rapamycin (mTOR), has shown phase I efficacy in NSCLC. METHODS Stage IIIb or IV NSCLC patients, with two or fewer prior chemotherapy regimens, one platinum based (stratum 1) or both chemotherapy and epidermal growth factor receptor ty...
Background and Aim: Moisturizers have important roles in the treatment of dry skin. Their safety has to be evaluated on human volunteers in order to assess their potential skin irritation. Measurements of skin biophysical parameters can be used as fast and noninvasive methods to assess any harmful effect of cosmetic formulations on the skin sites where those products are applied. Methods: Tw...
The thin skin of the left upper quadrant of the human abdomen has been studied by electron microscopy. Tissue removed with a high speed rotary punch was fixed in osmium tetroxide or potassium permanganate. The latter fixative in our preparations is superior to osmium for the demonstration of epidermal cell membranes and certain other membranous structures of the epidermis. The cytoplasmic membr...
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