law, the dose of drug delivered to the skin is controlled. Iontophoresis uses a small electric current to drive charged substances into the skin. Electromigration of ions during iontophoresis has also been shown to induce osmotic water flow and the convective movement of neutral or even charged molecules – a process termed electro-osmosis. It is generally held that the quantity of drug delivere...

background: extensive full-thickness burns require replacement of both epidermis and dermis. in designing skin replacements, the goal has been to re-create this model and make a product which has both essential components. methods: in the present study, we developed procedures for establishing confluent, stratified layers of cultured human keratinocytes on the surface of modified collagen-chito...

Replacement of a wounded or destroyed tissue is now technically possible using an in vitro method of tissue engineering. This method involves isolating and culturing human cells (autologous or not) in optimal conditions to form a reconstructed tissue with similar characteristics to its in vivo counterpart. Burn victims were the first patients to benefit from this method in 1981, wherein reconst...

Menopause is a key point moment in the specific aging process of women. It represents a universal evolution in life. Its initiation is defined by a 12-month amenorrhea following the ultimate menstrual period. It encompasses a series of different biologic and physiologic characteristics. This period of life appears to spot a decline in a series of skin functional performances initiating tissue a...

AIMS The objective of the study was to compare the efficiency of 20 MHz skin ultrasonography and 40 MHz conventional ultrasonography in the assessment of plaque psoriasis and to assess the efficiency of 40 MHz real-time sonoelastography in the early detection of steroid-induced skin atrophy in psoriatic plaques. PATIENTS AND METHODS Ultrasonographic blinded evaluation was performed on 16 plaq...

The enhancement of skin image in optical coherence tomography (OCT) imaging can help dermatologists to investigate tissue layers more accurately, hence the more efficient diagnosis. In this paper, we propose an image enhancement technique including speckle reduction, attenuation compensation and cleaning to improve the quality of OCT skin images. A weighted median filter is designed to reduce t...

Skin is a complex, multilayered material which is very difficult to study because of its great variability: it depends on individuals, but also on which body part one looks at. Even studying a small area, its behaviour varies with outside parameters (such as humidity) and aging. Let us describe its 3 main layers. 3 The epidermis: thickness 0.1mm, made of keratinocytes, which move from its botto...

Replacement of a wounded or destroyed tissue is now technically possible using an in vitro method of tissue engineering. This method involves isolating and culturing human cells (autologous or not) in optimal conditions to form a reconstructed tissue with similar characteristics to its in vivo counterpart. Burn victims were the first patients to benefit from this method in 1981, wherein reconst...

Background: Microcystic adnexal tumor is a rare sclerosing variant of ductal carcinoma of eccrine sweat glands which is highly invasive. This tumor is often misdiagnosed as other benign or malignant skin lesions and improper treatment is carried on and is associated with high recurrence rate. Case presen...