In this study, an optimization model is proposed to design a Global Supply Chain (GSC) for a medical device manufacturer under disruption in the presence of pre-existing competitors and price inelasticity of demand. Therefore, static competition between the distributors’ facilities to more efficiently gain a further share in market of Economic Cooperation Organization trade agreement (ECOTA) is...

a facility layout problem is concerned with determining the best position of departments, cells, or machines on the plant. an efficient layout contributes to the overall efficiency of operations. it’s been proved that, when system characteristics change, it can cause a significant increase in material handling cost. consequently, the efficiency of the current layout decreases or is lost and it ...

this paper investigates the effects of advertising, profitability, concentration and research & development on the market share of iranian great food and beverage industries during the period of 2000-2011. for this purpose, we used the more than 50 employee's statistics of industrial 4- digit firms and panel data technique for estimating the model. the main results of this paper reveal that, th...

An analytical design procedure to determine optimal noise hazard control strategies for industrial facilities is presented. Its objective is to determine a set of appropriate noise controls to eliminate or reduce noise levels so that workers' daily noise exposure does not exceed a permissible level. From a given noise control budget, engineering controls will be firstly implemented, followed by...

The Loanable funds theory Hypotheses: Individuals care only about real variables (output gains or losses, purchasing-power gains or losses). The marginal productivity of capital assets (MPK) is given and determined by the technical characteristics of the productive assets. It represents the gain, in terms of output, obtained by increasing the capacity of production by one additional capital ass...

A large panel of German municipalities is employed in order to investigate the dynamic fiscal policy adjustment of local jurisdictions using a VEC model which explicitly takes account of the intertemporal budget constraint. The results confirm the central role of expenditure adjustment, nevertheless a substantial part of adjustment is due to changes in intergovernmental transfers, in particular...

Optimum control of upstream pumping station in open channels with given constraint in downstream end is presented in this paper. The upstream control is capable of minimizing water level fluctuations in the channel in which the downstream pumping station causes an undesirable wave. The proposed method combines an unsteady non-uniform flow solver with shock-capturing capability, Fourier series a...

Nominal government debt, including the monetary base, is a residual claim to government surpluses. Thus, the value of Þat money can be determined in a completely frictionless economy, just like the price of stock. The main theoretical objection to this Þscal theory of the price level is that it mistreats the government’s intertemporal budget constraint. I show that the valuation equation for no...

The article investigates the investment and financial constraints for French, Hungarian and Slovenian farms using FADN panel data with different econometric estimation approaches. Farm gross investment is positively associated with real sales growth and cash flow implying the absence of soft budget constraint. Gross farm investment is positively associated with investment subsidies. Specific re...

INTRODUCTION New biosimilars of monoclonal antibodies are anticipated to bring significant cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently been approved in Europe in all indications held by reference rituximab (RTX), including rheumatoid arthritis, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. We analyzed the budgetary impact of the introd...