Inspiratory muscle weakness in patients with COPD is of major clinical relevance. For instance, maximum inspiratory pressure generation is an independent determinant of survival in severe COPD. Traditionally, inspiratory muscle weakness has been ascribed to hyperinflation-induced diaphragm shortening. However, more recently, invasive evaluation of diaphragm contractile function, structure, and ...

According to our previous theoretical study, sensor sensitivity is proportional to the cube of the side length of the diaphragm in a guided-wave optical pressure sensor consisting of a glass diaphragm and a single-mode waveguide on the diaphragm. Also, to obtain higher sensitivity, an aspect ratio of the diaphragm should be approximately 1 for two waveguide positions: the center and the edge of...

Elastic element mechanical pressure gages consisting diaphragm are basically used for the differential pressure measurement. In FODPS, diaphragm acts as a reflector. A flexible disc of plastic is used as a diaphragm to convert the measuring pressure to the deflection of diaphragm. Concentric corrugations are designed to linearise the deflections according to pressure. Reference and measuring pr...

Elastic element mechanical pressure gages consisting diaphragm are basically used for the differential pressure measurement. In FODPS, diaphragm acts as a reflector. A flexible disc of plastic is used as a diaphragm to convert the measuring pressure to the deflection of diaphragm. Concentric corrugations are designed to linearise the deflections according to pressure. Reference and measuring pr...

The mammalian diaphragm muscle is essential for respiration, and thus is one of the most critical skeletal muscles in the human body. Defects in diaphragm development leading to congenital diaphragmatic hernias (CDH) are common birth defects and result in severe morbidity or mortality. Given its functional importance and the frequency of congenital defects, an understanding of diaphragm develop...

A non-invasive device has been developed to monitor the diaphragm position and the blood flow in artificial heart assist devices equipped with a pressurised-air-driven diaphragm. Light scattering from the diaphragm is used as a mechanism for measuring. Information about the position of several points of the diaphragm can be obtained. The completely empty or filled situation can be detected and ...

Eventration of the diaphragm is a condition characterized by an attenuated but otherwise intact diaphragm. Twenty patients (age range: 2 days to 11 years) were treated for eventration of the diaphragm during a ten year period (19 85-1995). There were 11 girls and 9 boys with a mean gestational age of 37 weeks. 14 patients were born with cephalic presentation, 3 patients with breech deliver...

Cervical spinal cord injury (SCI) can dramatically impair diaphragm muscle function and often necessitates mechanical ventilation (MV) to maintain adequate pulmonary gas exchange. MV is a life-saving intervention. However, prolonged MV results in atrophy and impaired function of the diaphragm. Since cervical SCI can also trigger diaphragm atrophy, it may create preconditions that exacerbate ven...

Evidence for diaphragm injury in people with chronic obstructive pulmonary disease (COPD) has been reported, although the extent of injury and collagen accumulation post mortem have not previously been examined. In addition, it is not known whether the amount of injury and collagen are different in key regions of the diaphragm. The cross-sectional area of collagen and the percentage of abnormal...