cytogenetic studies were performed on 150 cases of down's syndrome (ds) in iran. the standard trisomy 21 was found in 132 (88 % ) and translocation-trisomy 21 (+21) in 18 (12%) patients, i.e., t(21,21) in 1(0.63%) and mosaicism in 17(11.33%) cases. the comparison of the frequencies for mosaicism between different populations such as denmark, hungary, egypt, iraq, india, australia and iran ...

abstract purpose - the aim of this paper is to describe the population ecology theory through fractal thinking, an emergent human operating system that is creative, adaptive, healthy, and evolutionary; furthermore, a parallel is drawn between the population ecology model and the fractal structure. top-down hierarchies are typically characterized by command and control systems of the authority t...

disorder in re-methylation process of homocysteine to methionine due to mutation in betaine homocysteine methyltransferase enzyme (bhmt) coding gene, leads to decrease in s-adenosyl methionine (sam) synthesis which takes part in dna methylation as a methyl donor. as a result, it can promote hypo-methylation of dna, chromosome instability, and chromosome missegregation, which in turn is one of t...

anxiety is one of the most common reactions that parents show while understanding their children's intellectual disability due to down syndrome. anxiety leads parents not to develop appropriate relations with their children, subsequently their psychological health are at risk. the present study was aimed to determine the effect of problem-focused coping strategy training on psychological sympto...

down syndrome (ds), trisomy 21, is the most common chromosomal syndrome that affects one in 600-800 live births. the advanced maternal age is the only well known risk factor to cause ds. our study revealed that many young mothers produced ds children than advanced age mothers in india. a total of 150 suspected ds cases were investigated cytogenetically. randomly selected 200 healthy families in...

the purpose of the present study is the comparison of the pattern of language perception in down syndrome (ds) children and typical children. to achieve the objective, nine subjects with ds (whose mental ages were 72-78 months and were drawn from five center of special education in the city of mashhad) and five typical children with the same mental ages were selected through random sampling; an...

objectives: one of the most effective methods to describe speech disorders is the measurement of speech intelligibility. the speech intelligibility indicates the extent of acoustic signals that correctly speaker produces and hearer receives. the purpose of this study was to investigate the speech intelligibility in the persian children with down syndrome, age range was 3 to 5 years, who had spo...

objectives: reading is a language skill based on visual modality which recently is addressed as a facilitator of expressive language in children with down syndrome. the aim was designing a whole word reading protocol and examining its effects on the language skills of children with down syndrome. methods: a whole word reading protocol was developed and was examined through a single-subject stud...