abstract background the present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (emla) to relief pain during spinal puncture in pediatric oncology patients. materials and methods sixty patients with malignancy candidate for spinal puncture were selected for this study. the patients were randomly allocated to two groups. group a had topical emla cream and...

conclusions this study does not support the use of emla for hsg. results there was no significant difference in the efficacy between emla and placebo creams in pain perception during the entire procedure. there was no significant difference in long term pain perception half an hour after the hsg performance. patients and methods eighty patients undergoing hsg as part of infertility evaluation w...

The efficacy of a topical anaesthetic formulation, EMLA 5% cream (Eutectic Mixture of Local Anaesthetics) in obtunding the pain produced by venepuncture, was determined in a double-blind randomized, cross-over study in 31 adult volunteers. Pain was registered on a 10-cm visual analogue scale. In each subject the mean pain score after treatment with EMLA was compared with that following placebo....

The author's study demonstrates that application of EMLA cream to treatment sites significantly reduces needle pain during Botox administration. Twenty patients receiving 200 Botox injections in the glabellar area experienced a 60% reduction in pain in EMLA-pretreated sites compared with that in matched control sites.

BACKGROUND Pregnancy is associated with reduced local anesthetic requirements and increased pain thresholds, possibly due to hormonal changes and activation of endogenous opioids. METHODS We compared the responses to a mechanical and an electrical stimulus in 30 pregnant women (pregnant group) scheduled for cesarean section and 30 healthy female volunteers (control group) matched for age. Pai...

BACKGROUND Hysterosalpingography (HSG) is considered as a primary test in infertility work up worldwide due to its reliability in evaluating abnormalities related to the uterus and fallopian tubes. OBJECTIVES To assess the efficacy of applying eutectic mixture of local anesthetics (lidocaine-prilocaine cream) (EMLA) on the uterine cervix in reducing pain during HSG. PATIENTS AND METHODS Eig...

OBJECTIVE The goal of this study was to compare the analgesic effect of sucrose with that of the combination of sucrose and the local anesthetic cream EMLA during venipuncture in preterm neonates. METHODS This randomized, double-blind prospective study included infants younger than 37 weeks' gestational age during 1 routine venipuncture for blood sampling. Each child randomly received either ...

BACKGROUND AND OBJECTIVES ADIAL ARTERY SPASM IS ONE OF THE MOST COMMON COMPLICATIONS OF TRANSRADIAL CORONARY ANGIOGRAPHY (TRA): the radial artery is prone to cathecholamine-induced contraction and radial pain during TRA could increase the sympathetic tone. The object of this study was to evaluate whether the eutectic mixture of local anesthesia (EMLA) cream, in addition to lidocaine infiltratio...