Synopsis In order to reduce the type I and II errors and obtain more accurate brain activation map, fMR images were statistically analyzed with uncorrected ttest, false discovery rate(FDR) and family-wise error rate(FWE) in the general linear model (GLM) through statistic parameter mapping software(SPM). This study compared and evaluated the power of thresholding correction methods with uncorre...

Introduction: Integration of single photon emission computed tomography (SPECT) and computed tomography (CT) scanners into SPECT/CT hybrid systems permit detection of coronary artery disease in myocardial perfusion imaging (MPI). Misregistration between CT and emission data can produce some errors in uptake value of SPECT images. The aim of this study was evaluate the influence...

Growing concern that most published results, including those widely agreed upon, may be false are rarely examined against rapidly expanding research production. Replications have only occurred on small scales due to prohibitive expense and limited professional incentive. We introduce a novel, high-throughput replication strategy aligning 51,292 published claims about drug-gene interactions with...

Bloodstream infections (BSIs) are a leading cause of death and have high health care-related costs worldwide (1). Hithertopublished studies showed that receiving timely and accurate information as to the nature of the causative agent(s) and its antimicrobial susceptibilities is of the utmost importance for clinical management as well as for implementation of the optimal targeted antimicrobial t...

Theorem proving is the systematic derivation of a mathematical proof from a set of axioms by the use of rules of inference. We are interested in a related but far less explored problem: the analysis and correction of false conjectures, especially where that correction involves nding a collection of antecedents that, together with a set of axioms, transform non-theorems into theorems. Most faile...

Olav Benjamin Vassend proposes two solutions to the “interpretive problem” of assigning nonzero probabilities hypotheses that are known be false. He argues verisimilitude interpretation (probability expresses degree belief hypothesis is closest truth) and counterfactual conditional on a false supposition) equivalent. While Vassend’s intuition about these basically correct, technical details his...

DWT and DCT domain watermarking schemes are not robust to geometric attacks such as rotation, scaling, and translation. Recent research has therefore focused on DFT-based watermarking because of its properties. In this paper, we generalize a circular watermarking scheme by embedding one watermark in lower frequencies, and another in higher frequencies. Our experiments show that if the circular ...