BACKGROUND It is well established that hypertensive patients with left ventricular (LV) hypertrophy have impaired diastolic filling. However, the impact of antihypertensive treatment and LV mass reduction on LV diastolic filling remains unclear. METHODS AND RESULTS Echocardiograms were recorded in 728 hypertensive patients with ECG-verified LV hypertrophy (Cornell voltage-duration or Sokolow-...

Age is an important determinant of Doppler indices of left ventricular diastolic filling in normal subjects. To define reference values and factors of importance to Doppler indices of left ventricular filling in subjects of similar age, 58 men and 76 women aged 50 years underwent Doppler echocardiography. All those taking part in the study were healthy. When gender was analysed in a multivariat...

AIM To study the left and right ventricular function and to assess the predictors of increased left ventricular (LV) filling pressure in dialysis patients with preserved LV ejection fraction. METHODS This study included 63 consecutive patients (age 57+/-14 years, 57% women) with end-stage renal failure. Echocardiography, including tissue Doppler measurements, was performed in all patients. Ba...

Abbreviations: A wave late-filling wave; CW continuouswave; dP/dtmax positive maximum first derivative of pressure, corrected for time; Ea arterial elastance; E/A ratio of the early and rapid-filling wave to the late-filling wave; E wave early and rapid-filling wave; LA left atrium atrial; LAP left atrial pressure; LV left ventricle/ventricular; LVEDA left ventricular end-diastolic area; LVEDP ...

Left atrial function in patients with hypertensive heart disease was compared with that in control subjects. In patients with hypertensive heart disease, the time constant of left ventricular relaxation was significantly greater than that in controls (54 +/- 18 vs 31 +/- 16 msec; p less than 0.01). The ratio of left ventricular filling volume before atrial contraction (left atrial reservoir vol...

Objectives—To investigate right ventricular diastolic function in systemic sclerosis (SSc) and its relation to clinical features of the disease. Methods—Seventy seven unselected SSc patients and 33 healthy subjects were submitted to echocardiography and echo Doppler study to assess left and right systolic as well diastolic function and to estimate maximal arterial systolic pulmonary pressure (P...

Three important parameters in designing a closed die for forging process are ratio of width to flash thickness, ratio of  height to billet diameter and the friction factor. In this paper the influences of these parameters on the required force for the forging and percentage of die filling were investigated. It was found that by controlling the flash dimension, the material loss is reduced and t...

We previously used the Doppler transmitral flow velocity ratio A/E (A = late ventricular filling peak velocity; E = early ventricular filling peak velocity) and the age-adjusted ratio A/E/Age to detect left ventricular filling abnormalities in untreated mild hypertension. This study is a double-blind assessment of the effect of combined alpha- and beta-blockade (labetalol) and beta-blockade alo...

OBJECTIVE To assess the early changes in left ventricular diastolic and systolic function due to anthracycline treatment. DESIGN A prospective study of cardiac function by radionuclide angiography in adults before and one month after the end of anthracycline treatment. PATIENTS 60 patients without cardiac disease treated with chemotherapy containing anthracycline. METHODS Cardiac function...