Description: Fluoride dentifrices were first introduced in the 1950s. [1] The first fluoride dentifrice contained stannous fluoride and was first marketed in 1955. Since then many studies have investigated the level of dose and the form of fluoride that is optimum in dentifrice formulations. Higher caries reduction was reported in the 70s in clinical trials that investigated the potency of usin...

INTRODUCTION Besides dental and skeletal fluorosis, excessive fluoride intake can also affect the central nervous system without first causing the physical deformities associated with skeletal fluorosis. With the existence of widespread endemic fluorosis in India, the possible adverse effect of elevated fluoride in drinking water on the Intelligence Quotient (IQ) level of children is a potentia...

objectives: this study aimed to assess the self-reported knowledge and attitude of dentists towards fluoride prescription. materials and methods: a questionnaire survey was conducted at the national annual dental congress in 2010 in tehran-iran. dentists’ level of knowledge about the preventive effects of systemic and topical administration of fluoride was assessed as well as their attitudes to...

BACKGROUND There are concerns that altered thyroid functioning could be the result of ingesting too much fluoride. Community water fluoridation (CWF) is an important source of fluoride exposure. Our objectives were to examine the association between fluoride exposure and (1) diagnosis of a thyroid condition and (2) indicators of thyroid functioning among a national population-based sample of Ca...

Wistar albino rats were exposed to 30 or 100 ppm fluoride in drinking water during their fetal, weanling and post-weaning stages of life up to puberty. Extent of lipid peroxidation and response of the antioxidant systems in red blood cells and plasma to prolonged fluoride exposure were assessed in these rats in comparison to the control rats fed with permissible level (0.5 ppm) of fluoride. Rat...

previous studies have indicated that there may be a relationship between the salivary fluoride concentrations and dental caries while the emphasis was on dental caries in permanent teeth. the aim of this study was to assess the prevalence of dental caries and its predictors in 3-6 year-old children in tehran, iran. the other objective of this investigation was to clarify a relationship between ...

Background and Aim: Previous studies revealed improved enamel caries resistance after laser irradiation. Present in vitro study evaluated the effect of Er,Cr:YSGG laser with or without topical fluoride application on microhardness of primary enamel after artificial demineralization. Materials and Methods: In this in vitro study, 35 primary molars with sound surfaces were bisected and randomly ...

Excessive fluoride intoxication plays an important role in the development of dental, skeletal and non-skeletal fluorosis. The aim of this study was to ascertain the toxic effect of excessive fluoride ingestion on the level of hydroxyproline and expression of type 1 collagen gene in rat bone and its amelioration by supplementation with Tamarindus indica fruit pulp extract. Forty albino rats wer...