نتایج جستجو برای: gastric cancer

تعداد نتایج: 973988  

ژورنال: کومش 2022

Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...

ژورنال: ابن سینا 2021
Abbasi, Abdollah, Afshari, Zeynab, Behroozi, Javad, Farhadi, Arezoo, Ghojaie, Manuchehr, Heidari, Mohammad Foad , Moosaie, Somayyeh, Nasrollahzadeh Sabet, Mehrdad, Shahbazi, Shirin,

Background and aims: Gastric cancer is a major public health issue as the fourth leading cause of cancer-related death in the world. Reactive oxygen species (ROS) induce DNA damage and this process plays an important role in gastric cancer development and progression. OGG1 is an essential component of the base excision repair pathway  that is required for the removal of oxidized guanine nucl...

Journal: :medical laboratory journal 0
khatoon heydari islamic azad university of damghan, iran razmin azarhoosh faculty of medicine, golestan university of medical sciences, iran vahideh kazeminejhad faculty of medicine, golestan university of medical sciences, iran fatemeh shakeri faculty of medicine, golestan university of medical sciences, iran alireza noroozi 5th azar hospital, golestan university of medical sciences, iran

abstract       background and objective: baba2 and hpa genes are involved in adherence of helicobacter pylori (h.pylori) to gastric mucosal tissue. this study aimed to investigate the frequency of these genes in isolates of h. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer.       methods: gastric biopsy samples were obtained from patients wit...

Journal: :گوارش 0
reza malekzadeh alireza sadjadi ayna riahi

gastric cancer is the most common gi cancer. it has a very high incidence rate in the northeastern iran.contrary to western countries and japan, the incidence of gastric cancer has been increasing in iran during the past two decades. helicobacter pylori infection is the most important risk factor for developing gastric cancer. however, the presence and influence of other environmental and genet...

ایری, نورالدین , ترابی زاده, ژیلا , عابدیان, سعید , قاسمی, مریم , مرجانی, جرن , میرابی, اراز محمد ,

Background and purpose: Gastric carcinoma is the second leading cause of cancer death worldwide and its incidence varies considerably according to geographical location. There are multiple etiologic factors such as infection with ËBV that play a role in carcinogenesis of gastric cancer, yet there is not enough evidence about pathogenesis of ËBV and its relationship with gastric cancer. Thus, ...

ژورنال: ارمغان دانش 2019

Abstract Background and Aim: Gastric cancer is one of the most common malignancies in the world. Genetic background is known to be one of the risk factors for gastric cancer. One of the genes that have been shown to be involved in various cancers, including gastric cancer, is the MCC gene. There are many SNPs in the MCC gene in the encoding and regulatory regions, one of which is rs9122, which ...

محمدی نژاد, پریسا, محمدی, ساغر, مغنی باشی, مهدی,

Background and purpose: Gastric cancer is the most common cancer associated with high mortality worldwide. One of the genes that is down-regulated in gastric cancer, is the SIRT3 that encodes the histone deacetylase enzyme. There is a variable number tandem repeat (VNTR) polymorphism in the intron 5 of SIRT3 gene and evidence shows that expression of SIRT3 gene increases by increase in the numb...

Journal: :acta medica iranica 0
f. safarpour d. safarpour

cancer of the stomach carries poor prognosis. surgery is the best treatment for gastric cancer. prediction of survival depends on the stage at the time of presentation. fluoroscopy, sonography, and computerized tomography are used for advanced gastric cancers staging, but they are not accurate enough to grade advanced gastric cancers. laparoscopic findings of lesions under direct vision, are ma...

Journal: :research in molecular medicine 0
omolbanin amjadi km 17 khazarabad road, khazar sq, sari, iran alireza rafiei km 17 khazarabad road, khazar sq, sari, iran abolghasem ajami km 17 khazarabad road, khazar sq, sari, iran vahid hosseini inflammatory diseases of upper gi tract research center, department of internal medicine, faculty of medicine, mazandaran university of medical sciences, sari, iran. hossein asgarian-omran molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medicalsciences, sari, iran.

inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, uv radiation, stress and etc. persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from t cells. these molecules (e.g. il-6, tnf-α, il-1β and il-17) are mostly pleiotropic cytokines involved i...

Journal: :iranian journal of radiation research 0
f. samiei department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran a. maddah safaei department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran e. esmati department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran a. alibakhshi department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran ms. mirai ashtiani department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran p. haddad department of radiation oncology, cancer institute, imam khomeini hospital, tehran, iran

background: gastric cancer is an important health problem across the world. chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. the purpose of this investigation was evaluation of response and tolerability to neoadjuvant eox regimen in locoregionally advanced gastric cancer. materials and methods: patients with locoregionally adv...

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