Background: Eosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, inc...

zygomycosis is a fulminant infection which usually afflicts patients who are immunocompromised by diabetes mellitus, malignancy or immunosuppressive therapy.l this disease is a rare but highly invasive fungal infection which occurs in organ transplant recipients. 2 mucormycosis confined to the gastrointestinal tract is an uncommon form of the disease. accounting for only seven percent of all mu...

case presentation we report a case of idiopathic colonic varices, diagnosed at a routine colonoscopy performed for nespecific abdominal disturbances in a female patient without liver disease or pancreatic conditions responsible for portal hypertension development. conclusions the development of colonic varices in the absence of a certain trigger represents a major issue for practitioners due to...

kawasaki disease is a systemic vasculitis of children. among gastrointestinal symptoms of this disease jaundice occurs uncommonly. we present a 23 month boy with icter and clinical hepatitis and final diagnosis of kawasaki disease.

Langerhans cell histiocytosis (LCH) is a rare histiocytic neoplasm. The clinical presentation and the disease extension are variable. LCH may involve single site, multiple sites within system, or systems. Gastrointestinal tract involvement most often observed in children with multisystem disease. Adult patients gastrointestinal extremely rare, only few cases have been reported. We present 45-ye...

Dear editor, We read the recent article of Rahmani et al entitled "Medical Management and Outcome of Paraquat Poisoning in Ahvaz, Iran: A Hospital-Based Study" in your journal (1). In their study they performed upper gastrointestinal (GI) endoscopy as a routine for all paraquat poisoned patients, because they considered paraquat a caustic agent and that it may cause severe mucosal injuries in e...

Lactoferrin, a major whey protein, is a red iron-binding protein present mainly in external secretions such as breast milk and in polymorphonuclear neutrophils. The presence of lactoferrin in body fluids is proportional to the flux of neutrophils and its assessment can provide a reliable biomarker for inflammation. In gastrointestinal diseases increased fecal lactoferrin is a sensitive and spec...

The hazards of living without a spleen were recognised by the paediatricians in the early 1960's when they focussed attention on the syndrome of fulminant sepsis, often due to pneumococcal infection, occurring in young children within the fIrst two years of splenectomy 1. A child, well at breakfast, might be febrile by lunch, comatose by evening and dead by the following morning. We now recogni...