background: the aim of the study was to determine the incidence of non-bacterial acute gastroenteritis associated with diar­rheal diseases in mazandaran province, northern iran. methods: a total of 400 symptomatic cases from patients with acute gastroenteritis from mazandaran province in iran were screened using eia method for the presence of rotavirus, adenovirus and astrovirus during 2005-200...

Background: Rotavirus infection is the most important cause of infectious, severe and dehydrating diarrhea death in children aged 5 under continues to have a significant impact on child morbidity mortality our countries. The aim this study was retrospectively determine prevalence rotavirus adenovirus patients presenting with gastroenteritis symptoms distribution pathogens according gender, age ...

A particular challenge to water safety in populous intertropical regions is the lack of reliable faecal indicators to detect microbiological contamination of water, while the numerical relationships of specific viral indicators remain largely unexplored. The aim of this study was to investigate the numerical relationships of FRNA-bacteriophage genotypes, adenovirus 41, and human adenoviruses (H...

background more than three million children in developing countries die from acute diarrhea annually. rotaviruses and adenoviruses are from the most important etiologic factors in acute gastroenteritis of children. objectives the aim of this study was to determine the prevalence of rotavirus and adenovirus among children with acute diarrhoea admitted to abuzar hospital in ahvaz (southwest iran)...

vaccines against the hiv-1 virus offers the best hope for eliminating hiv-associated mortality. recombinant adenovector type 5 (rad5) vaccine is a potential candidate for preventive vaccine strategies. in this study, we evaluated the rad5 prime/protein boost strategy in a murine model. we used rad5 harboring single hiv-1 genes. these genes, including gag (p24) and exon1 of tat, were amplified f...

A,t present, the laboratory confirmation of clinical adenovirus infection is generally made by either the isolation of virus in tissue culture or the finding of rising antibody tilers. Since it may take as long as two months to isolate an adenovirus and type it, and since the determination of rising titers is also laborious, it was hoped that some other method might be found for the rapid and r...

Abstract We engineered a novel adenovirus with modified capsid for use as an integrated anticancer gene therapy and to circumvent pre-existing immunity. The adenovirus, SynBAd, when administered intravenously, induced antigen-specific CD8 T cell immunity in the liver of mice (C57BL/6) splenic population effector memory cells at levels equivalent those by human Adenovirus serotype 5 (Ad5). Altho...

We develop candidate HIV-1 vaccines, of which two components, ChAdOx1.tHIVconsv1 (C1) and ChAdOx1.HIVconsv62 (C62), are delivered by the simian adenovirus-derived vaccine vector ChAdOx1. Aberrant adenovirus RNA splicing involving transgene(s) coding for SARS-CoV-2 spike was suggested as an aetiology rare adverse events temporarily associated with initial deployment adenovirus-vectored vaccines ...

background and aims: human adenoviruses can cause a diversity of clinical diseases, but there is no antiviral therapy formally approved by adenovirus infections. thus, antiviral agents derived from medicinal plants which are effective against adenoviruses infections are urgently required. therefore, this research was aimed to evaluate in vitro antiadenovirus activity of pomegranate (punica gran...