نتایج جستجو برای: haplotype analysis
تعداد نتایج: 2832840 فیلتر نتایج به سال:
For complex traits, most associated single nucleotide variants (SNV) discovered to date have a small effect, and detection of association is only possible with large sample sizes. Because of patient confidentiality concerns, it is often not possible to pool genetic data from multiple cohorts, and meta-analysis has emerged as the method of choice to combine results from multiple studies. Many me...
Abstract Selection not only increases the frequency of new-useful mutations but also remains some signals throughout the genome. Since these areas are often control economically important traits, identifying and tracking these areas is the most important issue in the animal genetics. The aim of this study was to detecting signals of selection in the genome of Turkmen horse using 70K SNP chip...
The probable ancestral haplotype for human apolipoprotein B (apoB) has been identified through immunological analysis of chimpanzee and gorilla serum and sequence analysis of their DNA. Moreover, the frequency of this ancestral apoB haplotype among different human populations provides strong support for the African origin of Homo sapiens sapiens and their subsequent migration from Africa to Eur...
conclusions this is the first research in comparing two genetic marker systems in p. variotti. we were prompted to explore polymorphisms utility in p. variotti with a look at using germplasm screening mapping of genome and strain improvement programs. results both systems discriminated 20 isolates of p. variotii successfully but were different in the amount of detectable polymorphism. using clu...
In this study phylogenetic relationship of the Jajrud River Brown trout Salmo trutta L. 1758 in the Namak Lake basin was analyzed using complete D-Loop sequence of the mitochondrial genome, compared to other Iranian populations of the species. The results clarified that Jajrud brown trout, similar to other Iranian brown trout populations belongs to the Danube phylogenetic lineage. The observed ...
Haplotype association analysis based on arbitrarily chosen markers might lower statistical power because of the larger number of degrees of freedom caused by irrelevant makers.On the other hand, an exhaustive search for all possible combinations of markers for haplotype analysis is computationally expensive for genome-wide association analysis.To improve power, we applied our recently developed...
Background: Heterogeneous mutations in the human coagulation factor IX gene lead to an X-linked recessive bleeding disorder known as hemophilia B. The disease is distributed worldwide with no ethnic or geographical priority. Materials and Methods: The aim of this study was to characterize the factor IX gene mutations in 28 unrelated Iranian hemophilia B patients. Polymerase chain reaction (PCR)...
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