Literature review shows that hepatitis C infection may increase the risk of non-hodgkin lymphoma. Reactivation of hepatitis B infection has been reported in patients with hairy cell leukemia after chemotherapy and/or splenectomy. We present hepatitis B surface (HBs) antigenemia and concurrent hepatitis C virus (HCV) seropositivity in a case of hairy cell leukemia. Key Words: Hairy cell leukemi...

In the absence of a hepatitis C virus (HCV) culture system, the use of a Semliki Forest virus replicon expressing genes encoding HCV structural proteins that assemble into HCV-like particles provides an opportunity to study HCV morphogenesis. Using this system, we showed that the HCV core protein constitutes the budding apparatus of the virus and that its targeting to the endoplasmic reticulum ...

conclusions real-time pcr and elisa showed high levels of production of 1a/jfh1 chimeric hcv in the huh7.5 cell culture. the constructed virus can be used for future studies, including the development of new hcv drugs and vaccines. background the e2 glycoprotein is an important encoded hepatitis c virus (hcv) protein that contains three different variable regions. objectives the aim of the pres...

conclusions although significant differences (p < 0.01) were observed in the frequency of ttmdv/sav between healthy controls and each of the hiv positive and hiv/hcv co-infected individuals, no significant difference was observed between hiv positive and hiv/hcv co-infected cases, which may be due to hiv associated immunodeficiency. this is the first time that ttmdv/sav is reported in hiv infec...

Abstract Background and Aims: The Hepatitis C Virus (HCV) is essentially hepatotropic but virus compartment has also been found in other important extra hepatic sites. Detection of HCV RNA in extra hepatic reservoirs such as peripheral blood mononuclear cells (PBMCs) is important for determining of disease progression and effective treatment. The present study aimed to determine of differe...

Hepatitis C virus (HCV) is extraordinarily diverse and uses entry factors in a strain-specific manner. Virus particles associate with lipoproteins, and apolipoprotein E (ApoE) is critical for HCV assembly and infectivity. However, whether ApoE dependency is common to all HCV genotypes remains unknown. Therefore, we compared the roles of ApoE utilizing 10 virus strains from genotypes 1 through 7...

Hepatitis C virus (HCV) is one of the leading causes chronic liver disease. Hepatocellular carcinoma (HCC) a major complication associated with HCV infection, significant mortality and morbidity rates. This study aimed to measure biochemical parameters RNA levels for detection severity hepatitis virus- hepatocellular carcinoma. The was conducted on 100 patients, ages ranging from 36 68 years p...

hepatitis c virus (hcv) infection has been associated with a plethora of immune and autoimmune perturbations. a variety of conditions ranging from endocrinopathies to different skin diseases has been described in hcv infection. the aim of this study was to investigate the prevalence and clinical significance of hcv infection in patients with graves’ disease (gd). a total of 55 patients with gd ...