background nowadays, it has been found that the mental state of caregivers may have a noticeable effect on both patient and caregiver’s health. this study was conducted to determine the burnout and general health status of the hematopoietic stem cell transplantation nurses in tehran, iran. methods in a cross-sectional study, burnout and general health status of 65 hematopoietic stem cell transp...

currently, hematopoietic stem cell transplantation (hsct) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful hsct. liver biopsy samples were taken from 14 patients (out of 25 patients) who underwent hsct. all patients met three criteria: negative hcv antibody...

Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...

The objective of the research was to determine effect educational intervention based on Bandura’s Social Cognitive Learning Theory care dependency and symptom management after hematopoietic stem cell transplantation.
 Methods. This randomized controlled trial conducted between January 2019 February 2020 at Hematopoietic Stem Cell Transplantation Center. All patients were randomly divided i...

background: myeloablative-allogeneic stem cell transplantation is a common way of treating various malignant and nonma-lignant diseases; but, it is associated with hazardous immediate and late complications. the majority of patients are not good candidates for high dose therapy because of old age, medical co-morbidities or previous heavy treatments. the donor stem cells can engraft in the recip...

thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. for β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...

A clinical study of lyophilized intravenous human immunoglobulin containing high-titer cytomegalovirus-neutralizing antibody for the treatment cytomegalovirus viremia after allogeneic hematopoietic stem cell transplantation

Background: This article reviews experimental and clinical studies in which neural injuries repaired with bone marrow stromal cells. History: Bone marrow contains two kinds of stem cells: hematopoietic and nonhematopoietic (stromal) stem cell. In vitro studies indicate that bone marrow stromal cells have the capacity of differentiation into other cells (such as neural cell) under treatment wit...

background: for adult all patients, the indications and appropriate timing of allogeneic hematopoietic stem cell transplantation (ahsct) continue to be debated. the primary aim of this single-institution study was to compare the results of our adult all patients that had been allografted with those reported in the current literature. subjects and methods: this study included 53 consecutive adul...