BACKGROUND Differentiated cells derived from pluripotent human embryonic stem (hES) cells offer the opportunity for new transplantation therapies. However, hES cells and their differentiated progeny express highly polymorphic MHC molecules that serve as major graft rejection antigens to the immune system of allogeneic hosts. To achieve sustained engraftment of donor cells, strategies must be de...

The present study addresses the following question: if among a group of decision making units, the decision maker is required to increase inputs and outputs to a particular unit in which the DMU, with respect to other DMUs, maintains or improves its current efficiencylevel, how much should the inputs and outputs of the DMU increase? This question is considered as a problem of inverse data envel...

Abbreviations: Bio-LC-ATB-BMPA, 4,4-O-[2-[ 2-[2-[2-[2-[6-(biotinylamino)hexanolyl]amino]ethoxy]exoxy]ethoxy]-4-(1-azi2,2,2-trifluoroethyl)benzoyl]amino-1,3-propanediyl]bis-D-mannose; HES, HEPES, EDTA sucrose; KRH buffer, Krebs-Ringer Hepes buffer; KHB, Krebs-Henseleit bicarbonate; PBS, phosphate-buffered saline; TBS-T, Tris-buffered saline, 0.1% Tween; Carboxy-SNARF-1, 5-(and 6-)carboxy-semi-na...

In this paper, we introduce the L-hypersurface method for use in linear inverse problems. The new method is intended to select multiple regularization parameters simultaneously. It is a multidimensional extension of classical L-curve method and hence does not require any speciic knowledge about the noise level or signal semi-norm. We give examples of the L-hypersurface method applied to the lin...

Prolonged propagation of human embryonic stem (hES) cells is currently achieved by coculture with primary mouse embryonic fibroblasts (MEFs) serving as feeder cells. Unlike mouse ES cells, adding growth factors such as leukemia inhibitory factor is insufficient to maintain undifferentiated hES cells without feeder cells. The presence of uncharacterized rodent cells or crude extracts imposes a r...

This paper proposes a reference signal extraction method for a semi-adaptive sound reproduction system based on semi-blind source separation (semi-BSS) under a noisy environment. Since the fluctuation of room transfer functions degrades the reproduced sound, we have proposed a semi-adaptive sound reproduction system that updates the inverse filters. However, in a noisy environment, it is diffic...

Via the semi-inverse method, variational principles are established for the Drinfeld-Sokolov-Wilson (DSW) equation. Based on the obtained variational formulations, exact solitary solution and exact singular periodic wave solution can be obtained using the variational approach.