In this review article determines the different analytical methods for quantitative establishment of Erlotinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical method development requires valid procedures and qualitative analysis in Pharmaceuticals dosage formulations human serum. This assessment explains that superiority HPLC/LC-MS reviewed is based on drugs formulations, (API), biolog...

Objective: To develop and validate simple, rapid, precise, accurate, and economical UV spectrophotometric and reverse phase high performance liquid chromatographic methods for the estimation of alogliptin benzoate (AGP). Methods: UV spectrophotometric method was performed using UV/Vis double beam spectrophotometer with a spectral bandwidth of 1 nm and 1.0 cm matched quartz cells. The maximum ab...

The hydrogenation of 4-nitrophenol (4-NP) has attracted much attention, since it is typically used as a model reaction for evaluating newly developed catalysts, but its mechanism still debated. Herein, Co(OH)2-modified CuO catalyst (Co(OH)2/CuO) was the reduction 4-NP to 4-aminophenol (4-AP) in an aqueous sodium borohydride (NaBH4) solution. investigated by UV-Vis spectroscopy (UV-Vis), high-pe...

dispersive liquid-liquid microextraction method (dllme) combined with high-performance liquid chromatography-ultraviolet detection (hplc-uv) was used to determine thiamine (b1), nicotinamide (b3) and pyridoxine (b6) in sour cherry juice. this method was rapid, simple and sensitive. separation was accomplished using a c18 column. the optimum chromatographic conditions were found to be: mobile ph...

Abstract Here, two important isoflavones present in Trifolium pratense, formononetin and biochanin A, were analyzed by high performance liquid chromatography coupled with UV (HPLC–UV). These are marker compounds anti-inflammatory, anti-cancer, anti-oxidant properties, also potent phytoestrogens that can be used hormonal therapies. Till date, no study regarding rapid identification quantificatio...

Reversed-phase HPLC and UV spectrophotometric techniques using water as solvent have been developed and validated for the simultaneous determination of amoxicillin and cloxacillin in capsules. For both techniques, the linearity range of 60.073x2013;140.0 µg/mL was studied. The spectrophotometric data show that non-derivative techniques, such as absorbance ratio and compensation, and ratio spect...

Solubility measurements using chemiluminescent nitrogen detection (CLND) has advantages of reduced compound requirement and increased throughput compared to UV-spectrophotometric and HPLC-based measurements. CLND with direct flow injection was evaluated for the measurement of thermodynamic solubility to support drug discovery. The limit of quantitation (LOQ), accuracy, and day-to-day reproducib...

A method is developed for the analysis of allantoin, gallic acid, dihydromelittoside, loganin, paeoniflorin, benzoylpaeoniflorin, and paeonol in Liuwei Dihuang tablets by high-performance liquid chromatography (HPLC)-UV-mass spectrometry (MS)-MS. Gradient elution with methanol-acetonitrile-water-formic acid solvent system is employed in the HPLC-electrospray ionization-MS study. The positive-io...