Prostatic carcinoma is the most commonly diagnosed tumor among men over 40 which results in over 30,000 deaths each year in the United States. Previous studies indicated that tumor cell lines produce and release several growth regulatory factors into their condition media and so far a number of human tumor cell-derived suppressor factors have been isolated that affect normal immune functions. I...

background : glioblastoma multiforme (gbm) or grade iv astrocytoma is the most common and lethal adult malignant brain tumor. several of the molecular alterations detected in gliomas may have diagnostic and/or prognostic implications, proteomics has been widely applied in various areas of science, ranging from the deciphering of molecular pathogen nests of discuses. method: we extracted protein...

background: essential oils are found to have multiple active components which can show in vitro cytotoxic action against various cancerous cell lines. this study reports the in vitro cytotoxic effects of the essential oil from artemisia absinthium l. (asteraceae) growing wild in iran. methods: water-distilled essential oil of a. absinthium collected from ardabil, north-western iran, was examine...

Introduction: The radioimmunoscintigraphy (RIS) has found widespread clinical applications in  tumor  diagnosis.  Human  epithelial  mucin,  MUC1,  is  commonly  over  expressed  in  adenocarcinoma including 80% of breast cancers and represents a useful target for RIS. The PR81  is  a  new  murine  anti-MUC1  monoclonal  antibody  that  was  found  to  react  with  the  membrane  extracts of se...

Isolation and identification of some potent anti-tumor compounds from medicinal plants, has motivated researchers to screen different parts of plant species for anti-tumor effects. It has been reported that several conifer posses cytotoxic activities on some human tumor cell lines. In this study, male and female branchlets or fruit of four different species of Iranian conifers (Juniperus Sabina...

background: neuroblastoma is the most common tumor in infancy and wilms’ tumor is the most common malignant tumor of kidney in childhood. both the tumors are usually within the differential diagnosis of each other. this study compares the clinical manifestations, sex and age distribution of childhood wilms’ tumor and neuroblastoma at one of tehran children hospitals. materials and methods: the ...

abstract gastrointestinal mesenchymal tumors are a group of tumors originating from the mesenchymal stem cells of the gi tract. digestive tract schwannomas are rare mesenchymal tumors which occur most frequently in the stomach. we report a 56-yearold woman who was examined endoscopically for dyspepsia which she had suffered from since 3 years ago. around gastric antral mass was seen. surgical r...

   In recent years, Hyperthermia has been used as an emerging technique for cancer treatment, especially for localized tumors. One of the promising cancer treatment approaches is magnetic nanoparticle (MNPs) Hyperthermia. In this theoretical work, the temperature distribution of a common tumor over the different sizes of Fe3O4 magnetic nanoparticles, namely 25, 50, 100, and 200 nm, was stud...

Objective(s): Controversial results have been reported regarding the anti-tumor properties of extracellular vesicles derived from mesenchymal stem cells (MSCs). The present study was conducted to evaluate whether secretome derived from Human Wharton’s jelly mesenchymal stem cells (hWJMSCs) may stimulate or inhibit breast cancer growth in vitro and in vivo.<st...