OBJECTIVE Whether neonatal hyperbilirubinemia and/or phototherapy increase the risk of autism spectrum disorder (ASD) is unclear. We sought to quantify the risk of ASD associated with elevated total serum bilirubin (TSB) levels and with phototherapy. METHODS In a retrospective cohort study of 525 409 infants born at ≥35 weeks' gestation in 15 Kaiser Permanente Northern California (KPNC) hospi...

CONTEXT With early discharge, many newborns have to be readmitted to hospital for hyperbilirubinemia to be treated, and this has been held responsible for the reappearance of kernicterus. OBJECTIVE To evaluate whether bilirubin levels in cord blood could predict neonatal hyperbilirubinemia that would require treatment, in full-term newborns up to their third day of life. TYPE OF STUDY Prosp...

BackgroundMany studies reported that copper, zinc and magnesium play important roles in the pathogenesis and development of neonatal hyperbilirubinemia. Exchange transfusion and intensive phototherapy are known two modalities of therapy for severe neonatal hyper bilirubinemia, but the effect of them on those trace elements is unknown.Materials and MethodsCopper, Zinc and Magnesium serum levels ...

Objective: To compare the frequency of complications (hyperthermia, skin eruption, dehydration) LED phototherapy and fluorescent in management indirect hyperbilirubinemia neonates Material methods: This randomized control study was carried out from 1st June 2015 to 31 December 2016 at NNU The Children`s Hospital Lahore using Non probability consecutive sampling technique after getting informed ...

A 3 kg baby was delivered by cesarean section after prolonged labor. He had massive subgaleal hematoma. He developed anemia requiring packed cell transfusions and hyperbilirubinemia requiring a total of seven exchange transfusions and highly intensive phototherapy. There were no adverse complications of the hyperbilirubinemia or the exchange transfusion.

Context: Hyperbilirubinemia is a common cause for diagnostic work-up and therapeutic intervention in neonates needs convenient, quick, safe treatment modality. Phototherapy the most neonatal jaundice; however, complementary still needed. Despite identification of enzymatic pathways bilirubin catabolism, few pharmacological interventions have been found to be effective reducing bilirubin, along ...

Although neonatal jaundice is common, acute bilirubin encephalopathy and kernicterus (i.e., chronic bilirubin encephalopathy) are rare. Universal screening for neonatal hyperbilirubinemia is controversial. The American Academy of Pediatrics recommends universal screening with bilirubin levels or targeted screening based on risk factors. However, the U.S. Preventive Services Task Force and the A...

bakground: phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia as well as the management of subsequent complications in the newborn.  however, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions.   objective: this study was under-taken to investigate pho...