A modified passive cutaneous anaphylaxis test and an ELISA were used to identify IgE in calves vaccinated (sensitized) with chlorine dioxide-inactivated bluetongue virus (BTV) and in calves inoculated with infectious BTV. The levels of IgE were greatest in the vaccinated calves after challenge with infectious virus, which correlated with development of clinically apparent dermatitis and stomati...

: Aspirin (ASA) hypersensitivity comprises types I to III (Cox-1 mediated) and types IV and V (IgE antibody mediated). Rapid, low-dose (81-325 mg/day) ASA desensitization regimens are known to be useful in establishing ASA tolerance in patients with coronary artery disease and coexisting ASA/nonsteroidal anti-inflammatory drug hypersensitivity. We document 3 cases in Vietnam of desensitization ...

Introduction The aminoglycosides are a group of antibiotics widely used, adverse reactions to these drugs have frequently been reported, mainly toxic (ototoxicity and nephrotoxicity); hypersensitivity reactions that occur more often are contact dermatitis, generally to ophthalmic and otic Neomycin and Gentamicin preparations, however, hypersensitivity reactions mediated by IgE, have been recent...

BACKGROUND The pathogenesis of atopic dermatitis (AD) is still not completely understood. AD is characterized by the presence of clinical symptoms of both IgE antibody-mediated immediate hypersensitivity and specific T lymphocyte-mediated delayed hypersensitivity. OBJECTIVE To evaluate the immunological mechanisms involved in children with acute AD lesions. MATERIAL AND METHODS Ten children...

Drug-induced hypersensitivity reactions encompass a variety of different clinical phenotypes ranging from harmless rashes to fatal reactions. They can be classified into allergic (i.e. drug allergy) and non-allergic hypersensitivity). Drug allergies in turn either antibody (e.g. IgE) or T cell-mediated. One the diagnostic tools for vitro detection allergy is lymphocyte transformation test (LTT)...

The mechanism of penicillin immediate hypersensitivity reactions has not been completely elucidated. These reactions are generally considered to be mediated by IgE, but penicillin-specific IgE could not be detected in most cases. This study demonstrated that penicillin was able to cause vascular hyperpermeability in a mouse model mimicking clinical symptoms of penicillin immediate hypersensitiv...

Food protein induced enterocolitis syndrome (FPIES) is a food-related gastrointestinal hypersensitivity disorder, probably non-IgE-mediated. Over the years, various diagnostic criteria have been proposed to identify FPIES. In the last few years, there was an increased interest from researchers about FPIES's syndrome, that frequently brought to discover new aspects of this disease. We describe a...

Background: The ancient concept of “intrinsic” and “extrinsic” asthma has evolved in line with growing scientific knowledge the use new clinical diagnostic tools. Objective: present study aims to evaluate non-IgE-mediated immunoreactivity against common allergens, asthmatic patients without evidence IgE-mediated hypersensitivity these allergens. Methods: A group 127 outpatients, were submitted ...

BACKGROUND Allergic reactions after ingestion of fermented soybeans have rarely been reported. Fermented soybeans were recently reported to be a causative food of IgE-mediated, late-onset anaphylaxis without early phase responses. The objectives of our study are to clarify the clinical and laboratory features and to characterize the allergens in allergy due to fermented soybeans. METHODS Seve...