نتایج جستجو برای: indicating method

تعداد نتایج: 1791594  

2013
Przemysław Zalewski Judyta Cielecka-Piontek Piotr Garbacki Anna Jelińska Marta Karaźniewicz-Łada

The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in the presence of degradation products formed during forced degradation studies. An isocratic RP-HPLC method was developed with a Lichrospher RP-18 (250 mm × 4.6 mm, 5 μm) column and the mobile phase composed of 45 volumes of acetonitrile and 55 volumes of mixture composed o...

Journal: :Journal of chromatographic science 2013
B V Rami Reddy G Jyothi B S Reddy N V V S S Raman K Subhash Chander Reddy C Rambabu

A novel stability-indicating reversed-phase high-performance liquid chromatographic (HPLC) method has been developed for the quantitative determination of darunavir ethanolate, an HIV-1 protease inhibitor. The chromatographic separation was achieved using an X-Bridge C18 (150 × 4.6 mm × 3.5 µm) HPLC column in isocratic mode employing 0.01M ammonium formate (pH.3.0) buffer and acetonitrile in th...

2013
Deepti Jain Rajiv Gandhi P. K. Basniwal S. Panda S. Jain

A sensitive, stability-indicating liquid-chromatographic method for analysis of tamsulosin in the presence of its degradation products has been developed and validated. Efficient chromatographic separation was achieved on a C18 column with a simple isocratic mobile phase consisting methanol: 50 mM phosphate buffer (pH 7.8, ratio 80:20) at a flow rate of 1 ml/m. The linearity of the method was e...

The objective of the study was to develop a simple, specific and stability-indicating HPLC method for the simultaneous determination of creatine phosphate sodium (CPS) and its related substances in pharmaceutical formulation. Separation of creatine phosphate sodium from its major process impurities and degradation products was achieved on a Hypersil BDS C18 column (250 × 4.6 mm, 5 μm) with an a...

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