background : ulcerative colitis an inflammatory bowel disease (ibd) and chronically idiopathic immune related that associates with extraintestinal manifestations such as arthritis. despite of the highly specificity ofanti-cyclic citrullinated peptide (ccp) antibodies for rheumatoid arthritis, their role in ibd remains unclear . there are only a few studies on the prevalence of anti-ccp antibodi...

alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

introduction due to limitation of colonoscopy in assessing the entire bowel and patients’ intolerance in inflammatory bowel disease (ibd), in the current study, we aimed to prospectively compare the accuracy of 99m tc(v)-dimercaptosuccinic acid (dmsa) and fecal calprotectin with ileocolonoscopy as new methods for localizing inflammations. methods current prospective study conducted between 2012...

background: pelvic inflammatory disease is one of the most serious infection and one of the important and life threatening complications of it is tubo-ovarian abscess. this infection with intrauterine insemination (iui) is rare. we report a case of ruptured tubo- ovarian abscess after (iui). case: a 27 years old woman was referred to our center with acute abdominal pain and fever one week after...

background: in some studies inflammatory bowel disease (ibd) and celiac disease were considered to be associated and some belive that this association may influence the prognosis of ibd. however, there is a cosiderable controversy regarding this association. therefore ,we aimed to assess the association of these two common digestive diseases and evaluate the complications of this association. m...

background and aims: cytomegalovirus (cmv) infection is very common in the population. virus belongs to the family herpesviridae, whose representatives are characterized by the ability to cause the human body's latent persistent infections. the goal of the study is to assess the cmvv infection frequency and pcr method in the choice of cmv in inflammatory eye disease, comparing with cmv pre...

background inflammatory bowel disease (ibd) may begin as early as the first year of life. the objective of the present study was to determine the characteristics and clinical course of children with early-onset ibd. materials and methods the records of patients with ibd admitted to children medical center hospital during 2003-2006 were screened for those with disease onset before the first year...

background worldwide, the incidence of inflammatory bowel disease (ibd) is increasing. this study aims to evaluate the diagnostic value of two serological markers, atypical perinuclear anti-neutrophil cytoplasmic antibodies (atypical-p-anca) and anti-saccharomyces cerevisiae antibodies (asca), with the intent to determinetheir relationship to ulcerative colitis (uc) and crohn's disease (cd), in...

Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...

a 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. only mesalamine kept ulcerative colitis under control. in physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. computed tomography scan ...