AIMS A possible addiction mechanism has been represented by altered functional connectivity (FC) in the resting state. The aim of this study was to evaluate the FCs of the insula and nucleus accumbens among subjects with Internet gaming disorder (IGD). METHODS We recruited 30 males with IGD and 30 controls and evaluated their FC using functional magnetic imaging scanning under resting, a stat...

The insular cortex of macaques has a wide spectrum of anatomical connections whose distribution is related to its heterogeneous cytoarchitecture. Although there is evidence of a similar cytoarchitectural arrangement in humans, the anatomical connectivity of the insula in the human brain has not yet been investigated in vivo. In the present work, we used in vivo probabilistic white-matter tracto...

Systematic reviews of neuroimaging studies confirm stimulus-induced activity in response to verbal and non-verbal self-referential processing (SRP) cortical midline structures, temporoparietal cortex insula. Whether SRP can be causally modulated by way non-invasive brain stimulation (NIBS) has also been investigated several studies. Here we summarize the NIBS literature including 27 task-based ...

Abstract Background Although several brain networks play important roles in cervical dystonia (CD) patients, regional homogeneity (ReHo) changes CD patients have not been clarified. We investigated to explore ReHo at rest and analyzed its correlations with symptom severity as measured by Tsui scale. Methods A total of 19 21 gender-, age-, education-matched healthy controls underwent fMRI scans ...

The insular cortex is one of the brain regions that show consistent abnormalities in both structural and functional neuroimaging studies of schizophrenia. In healthy individuals, the insula has been implicated in a myriad of physiologic functions. The anterior cingulate cortex (ACC) and insula together constitute the salience network, an intrinsic large-scale network showing strong functional c...

Interoceptive awareness is defined as the awareness of stimuli originating inside one’s own body such as the heartbeat. The emergence of new brain imaging techniques like functional magnetic resonance imaging (fMRI) or magnetic resonance spectroscopy (MRS) has increased our knowledge of neural substrates underlying interoceptive awareness. In particular, the bilateral brain structure of the ins...