نتایج جستجو برای: intestinal microbiota

تعداد نتایج: 153962  

2015
Lea-Maxie Haag Britta Siegmund

Crohn's disease (CD) is a chronic, relapsing inflammatory disorder that can occur anywhere along the gastrointestinal tract. The precise etiology of CD is still unclear but it is widely accepted that a complex series of interactions between susceptibility genes, the immune system and environmental factors are implicated in the onset and perpetuation of the disease. Increasing evidence from expe...

2015
Tian-Xing Liu Hai-Tao Niu Shu-Yang Zhang

OBJECTIVE This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target. DATA SOURCES This study was based on data obtained from PubMed and EMBASE up to June 30, 2015. Articles were selected using the following search terms: "Intestinal microbiota", "trimethylamine N-oxide (TMAO)", "trime...

2015
Curtis D. Klaassen Julia Yue Cui

Information on the intestinal microbiota has increased exponentially this century because of technical advancements in genomics and metabolomics. Although information on the synthesis of bile acids by the liver and their transformation to secondary bile acids by the intestinal microbiota was the first example of the importance of the intestinal microbiota in biotransforming chemicals, this revi...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2015
Curtis D Klaassen Julia Yue Cui

Information on the intestinal microbiota has increased exponentially this century because of technical advancements in genomics and metabolomics. Although information on the synthesis of bile acids by the liver and their transformation to secondary bile acids by the intestinal microbiota was the first example of the importance of the intestinal microbiota in biotransforming chemicals, this revi...

2015
Tomoyo Taniguchi Eiji Miyauchi Shota Nakamura Makoto Hirai Kazutomo Suzue Takashi Imai Takahiro Nomura Tadashi Handa Hiroko Okada Chikako Shimokawa Risa Onishi Alex Olia Jun Hirata Haruyoshi Tomita Hiroshi Ohno Toshihiro Horii Hajime Hisaeda

Gastrointestinal symptoms, such as abdominal pain and diarrhea, are frequently observed in patients with Plasmodium falciparum malaria. However, the correlation between malaria intestinal pathology and intestinal microbiota has not been investigated. In the present study, infection of C57BL/6 mice with P. berghei ANKA (PbA) caused intestinal pathological changes, such as detachment of epithelia...

Fermented foods containing probiotic bacteria have been used for many years to improve the health or treatment of some diseases. Nowadays, the Therapeutic properties of probiotics are becoming more and more obvious to everyone, insofar as in recent years, more attention has been paid to the potential relation between gut microbiota and mental health. Several studies have shown that intestinal m...

Journal: :The journal of medical investigation : JMI 2016
Keiko Kataoka

The role of the intestinal microbiota in human health is gaining more attention since clear changes in the composition of the intestinal bacteria or environment are seen in patients with inflammatory bowel disease, allergy, autoimmune disease, and some lifestyle-related illnesses. A healthy gut environment is regulated by the exquisite balance of intestinal microbiota, metabolites, and the host...

2018
Jannigje G. Kers Francisca C. Velkers Egil A. J. Fischer Gerben D. A. Hermes J. A. Stegeman Hauke Smidt

The initial development of intestinal microbiota in poultry plays an important role in production performance, overall health and resistance against microbial infections. Multiplexed sequencing of 16S ribosomal RNA gene amplicons is often used in studies, such as feed intervention or antimicrobial drug trials, to determine corresponding effects on the composition of intestinal microbiota. Howev...

Journal: :Gut microbes 2014
Joann Romano-Keeler Daniel J Moore Chunlin Wang Robert M Brucker Christopher Fonnesbeck James C Slaughter Haijing Li Danielle P Curran Shufang Meng Hernan Correa Harold N Lovvorn Yi-Wei Tang Seth Bordenstein Alfred L George Jörn-Hendrik Weitkamp

Fecal sampling is widely utilized to define small intestinal tissue-level microbial communities in healthy and diseased newborns. However, this approach may lead to inaccurate assessments of disease or therapeutics in newborns because of the assumption that the taxa in the fecal microbiota are representative of the taxa present throughout the gastrointestinal tract. To assess the stratification...

2016
Benoit Chassaing

nflammatory bowel disease (IBD) is a group of chronic Iintestinal inflammatory disorders, mainly comprising Crohn’s disease (CD) and ulcerative colitis, which together affect 1.4 million people in the United States and 2.2 million people in Europe. Many studies have shown the presence of an altered intestinal microbiota composition in IBD patients, as well as in mouse models of chronic intestin...

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