Oral controlled drug delivery systems represent the most popular form of sustained drug delivery systems for the obvious advantages of oral route of drug administration. Such systems release the drug with constant or variable release rates. The oral controlled release systems shows a typical pattern of drug release in which the drug concentration is maintained in the therapeutic window for a pr...

In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...

In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...

Mucoadhesive microbeads of low methoxyl pectin were prepared, either alone or in combinations with hydroxypropyl methyl cellulose, sodium carboxymethyl cellulose, methyl cellulose and carbopol 934P, by ionotropic gelation. The influence of copolymers on mucoadhesivity, microbeads characteristics and in vitro drug release was investigated. Spherical microbeads with 78.69±0.59 to 85.84±0.78% drug...

The goal of this study was to develop floating microspheres that could be used as gastroretentive systems for the delivery of anthocyanins (ACNs). These compounds are absorbed in the stomach and small intestine, and insufficient residence time in these organs could result in limited absorption and contribute to degradation. The microparticles containing freeze-dried haskap berry extract (321.96...

This study's aim is to characterize aerosolization properties of ciprofloxacin loaded kappa-carrageenan microspheres for pulmonary delivery. Ciprofloxacin-carrageenan by ionotropic gelation were prepared and characterized moisture content, yield, drug loading, efficiency, properties, activity stability. Characteristics showed spherical microspheres, smooth size below 2µm, content <4%, yield ...

gum was extracted and characterized by material, proximate pasting properties.Terminalia in combination with sodium alginate at varying concentrations(0-80 %w/v) used preparing the microbeads ionotropic gelation using zincchloride as chelating agent. The were evaluated shape,size, swelling, buoyancy, entrapment efficiency, drug release profiles andkinetic modelling. spherical to ovoid shape siz...

Nanoparticles are currently becoming one of the important parts for various segments. Much more process/application becomes effective or economical and time-saving because nanoparticles. Polymers with distinct characteristics widely used but nature-origin polymer has properties that make a polymeric material Many methods were successfully evaluated to prepare chitosan nanoparticles loading comp...

In recent years, Nanochitosan and chitosan encapsulated Zinc oxide nanoparticles have gained tremendous attention related to their unique properties such as exhibit antimicrobial properties. On that account, synthesis of nanochitosan zinc by ionotropic gelation method fascinating eco-friendly, biodegradability, biocompatibility, bioactivity, nontoxicity polycationic nature. Impact on biological...