UNLABELLED Ex vivo autoradiographs of healthy kidney tissue from patients who received (111)In-DTPA-octreotide (DTPA is diethylenetriaminepentaacetic acid) before nephrectomy showed very heterogeneous radioactivity patterns in the kidneys. The consequences of the reported inhomogeneities have been evaluated for radionuclide therapy with (90)Y- DOTA-Tyr(3)-octreotide (DOTA is 1,4,7,10-tetraazacy...

Introduction: Nowadays,  considerable developments  in  the field  of  radiotherapy have  been  achieved.  They  include  the  advances  made  in  the  equipments  and  treatment  planning  techniques  which  require  highly complex calculations. Such achievements have made it possible to treat cancer patients not only  with  higher  radiation  dose  but  also  with  higher  precision  and  con...

Introduction Dosimetric accuracy is a major issue in the quality assurance (QA) program for treatment planning systems (TPS). An important contribution to this process has been a proper dosimetry method to guarantee the accuracy of delivered dose to the tumor. In brachytherapy (BT) of gynecological (Gyn) cancer it is usual to insert a combination of tandem and ovoid applicators with a complicat...

Introduction: Polymer gels are modern dosimeters providing three dimensional dose distributions. These dosimeters can be used in brachytherapy in which the tumor dimension is relatively small and the dose gradient is high. In this study, the ability of the MAGICA polymer gel was investigated for assessing the absolute dose values as well as the dose distribution of low dose rate (LDR) Ir-192 wi...

Aim: The purpose of this study was to make a comparison between measured and calculated physical wedge dose distributions using the superposition algorithm. Settings and Design: The accurate determination of absorbed dose is important radiotherapy because of the relatively steep sigmoidal dose response curves for both tumor control and normal-tissue damage. Materials and Methods: High-energy ph...

I T HAS been recognized that intracavi-tary irradiation is essential in the treatment of carcinoma of the uterine cervix. Since the beginning of the present century3 many applicators have been used to irradiate the uterus and vagina and later several afterloading techniques have been de-scnibed. " 4 Some of the techniques involve the use of remote control5 " and linear distribution of the sourc...

introduction: polymer gels are modern dosimeters providing three dimensional dose distributions. these dosimeters can be used in brachytherapy in which the tumor dimension is relatively small and the dose gradient is high. in this study, the ability of the magica polymer gel was investigated for assessing the absolute dose values as well as the dose distribution of low dose rate (ldr) ir-192 wi...

introduction: nowadays,  considerable developments  in  the field  of  radiotherapy have  been  achieved.  they  include  the  advances  made  in  the  equipments  and  treatment  planning  techniques  which  require  highly complex calculations. such achievements have made it possible to treat cancer patients not only  with  higher  radiation  dose  but  also  with  higher  precision  and  con...

bebig ruthenium-106 ophthalmic plaques have been used for treatment of uveal melanoma, retinoblastoma, melanoma of the iris and other special applications for many years. the plaques consist of a thin film of 106ru, a beta emitter, encapsulated in pure silver. the present work proposes a new mathematical eye model for ophthalmic brachytherapy dosimetry. this new model includes detailed descript...