BACKGROUND Low-level exposure to lead and to chronic stress may independently influence cognition. However, the modifying potential of psychosocial stress on the neurotoxicity of lead and their combined relationship to aging-associated decline have not been fully examined. OBJECTIVES We examined the cross-sectional interaction between stress and lead exposure on Mini-Mental State Examination ...

conclusions the results of this study showed that exposure to lead increased the activity of g6pd in the rat erythrocytes, perhaps resulting in an up regulation of the enzyme to detoxify lead. materials and methods in this study 14 albino rats were divided into two groups of seven animals. the treated group was exposed to 2% lead acetate in the drinking water during eight weeks. the control gro...

The effectiveness of glycine in treating experimental lead intoxication was examined in rats. Male Wistar rats were exposed to 3 g/L lead acetate in drinking water for 5 weeks and treated thereafter with glycine (100 and 500 mg/kg, orally) once daily for 5 days or glycine (1000 mg/kg, orally) once daily for 28 days. The effect of these treatments on parameters indicative of oxidative stress (gl...

AIMS The present study was aimed at investigating chronic exposure to lead and ethanol, individually and in combination with blood oxidative stress leading to possible brain apoptosis in rats. METHODS Rats were exposed to lead (0.1% w/v in drinking water) or ethanol (1 and 10%) either individually or in combination for four months. Biochemical variables indicative of oxidative stress (blood a...