background polypeptide hormone leptin suppresses inflammation in the heart muscle and protects heart from diseases. the purpose of this study is to evaluate the relationship between leptin and troponin serum levels with cardiac involvement in patients with major beta thalassemia. materials and methods in this cross-sectional study, 70 children with major thalassemia were selected. two ml blood ...

nitric oxide (no) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. recent evidences suggest that no may act as an endocrine molecule. the aim of this review is considering available literature on endocrine roles of no and/or its metabolites, i.e. nitrite and nitrate. existing data suggest the idea that no is a hormone that after production i...

Objective: Obesity is a medical problem that increases the risk of health problems like diabetes. Hormones secreting from fat tissue, Leptin, are correlated with body mass index. Leptin reduces the personchr('39')s appetite by acting on specific centers of their brain to reduce their urge to eat. And insulin, a hormone produced by the pancreas, is essential for regulating carbohydrates and the ...

Leptin, a potent anorexigenic hormone secreted primarily by adipocytes, is known to be expressed in the anterior pituitary. Studies in our laboratory found leptin proteins and mRNA predominantly in somatotropes in normal male and cycling female rats. In contrast, leptin expression predominated in gonadotropes during pregnancy and lactation. Leptin expression varied with the cycle and was enhanc...

What is hunger? How do we know how much to eat? And what happens if not eat enough? To survive, the human body must have energy reserves available in form of fat. Using a hormone called leptin, fat tissue regularly sends messages brain about body’s reserves. When receives lot it tells body, “you are full, stop eating.” In certain situations, like obesity and pregnancy, less sensitive leptin—so ...

Submit Manuscript | http://medcraveonline.com Hunger and satiety are generally regulated by the central nervous system (CNS) via the gut-brain axis and a number of hormones play critical roles in body weight management [3,4]. Among these hormones, the three most important hormones are leptin, ghrelin and insulin [5]. Leptin is a hormone secreted by fat cells which sends negative feedback signal...

ABSTRACT Physical activity is known to influence and regulate leptin hormone secretion, which assists in the regulation of body weight and energy homeostasis. The purpose of the present study was to investigate the effects of a single session of concurrent exercise on leptin levels and insulin resistance, until 24 h post-exercise. Ten male subjects (22.9±1.7 years) healthy volunteer perf...

INTRODUCTION Serum leptin levels have been examined in various cancers, with conflicting results. However, there is limited information regarding serum leptin levels and insulin resistance in gastric cancer patients. Therefore, we aimed to investigate serum leptin levels, performance status, insulin levels and insulin resistance in patients with gastric cancer. In addition, we examined the rela...

introduction: leptin is an adipocyte-derived hormone. exogenous leptin allows the recovery of the reproductive function. in humans, leptin correlates positively with the body mass index (bmi). the aim of this study was to investigate the association of leptin with the toxic effects of iron overload. methods: 219 major beta thalassemic patients (119 men, 100 women) and 137 non thalassemic indivi...