A RECENT report from Scandinavia (Dhuner et al., 1956) describes a clinical trial of Carbocaine in which 652 cases were injected with results which the authors describe as raising " expectations that Carbocaine may prove to be of great value as a local anaesthetic drug." It was found that, when no adrenaline was used, anaesthesia lasted longer with Carbocaine than with lignocaine (Xylocaine), f...

Analgesic effects were conducted with 2% lignocaine hydrochloride (LH), 2% lignocaine hydrochloride with adrenaline (LHA) and 0.5% bupivacaine hydrochloride (BH) in calves of both sexes. Analgesic drugs were injected into caudal epidural space in 30 apparently healthy calves of below one year of age. A total of 30 analgesic trials were done, where heart rate, respiration rate and rectal tempera...

We have studied the effects of extradural administration of 2% lignocaine at the L3-4 interspace on somatosensory evoked potentials recorded in the cervical extradural space before corrective surgery for idiopathic adolescent scoliosis. Eight patients in whom the equivalent volume of 0.9% sodium chloride solution was administered into the lumbar extradural space acted as a control group. Lignoc...

Accessible online at: www.karger.com/journals/res Fiberoptic bronchoscopy is widely employed by chest physicians around the world and enjoys a remarkable record of safety in a broad spectrum of patiens with a variety of clinical problems. Whether the bronchofiberscope is introduced transorally or transnasally, topical anesthesia is well tolerated. Cocaine, benzocaine, tetracaine, and lignocaine...

OBJECTIVES Although articaine has been recommended for providing an improved local anaesthetic effect in patients presenting for dental treatments, a relevant meta-analysis has been lacking. Despite articaine's popularity, there is contradictory evidence to support the claims. The aim of this systematic review was to compare the efficacy and safety of articaine with lignocaine in maxillary and ...

A common drawback of propofol is pain on injection and lignocaine is commonly mixed with propofol to reduce its incidence and severity. In this study we sought to compare the effectiveness of propofol medium chain and long chain triglyceride (MCT/LCT ) alone in comparison to propofol medium chain and long chain triglyceride (MCT/ LCT) premixed with lignocaine in preventing propofol pain on inje...

In cats with permanently implanted catheters in the lumbar epidural space, the typical responses to the epidural administration of lignocaine and amethocaine were a flaccid paralysis of the hind limbs and a block of the flexion reflex. The responses to periodic injections of lignocaine were consistent up to fourteen weeks after surgery. The effects of lignocaine were enhanced (1) when the total...

In a double-blind, double-dummy study, the efficacy of topical 5% EMLA cream was compared with that of lignocaine infiltration in alleviating the pain of arterial cannulation. Forty unpremedicated adults were allocated randomly to four groups to receive EMLA cream alone, EMLA and 0.9% saline infiltration, EMLA and 1% lignocaine infiltration or placebo cream and 1% lignocaine infiltration. Follo...

Background: Propofol is the most commonly used induction agent, but causes pain on injection in many patients. Various techniques have been tried and tested for reducing pain due to propofol injection with different results. Objective: To compare the use of pretreatment with granisetron in comparison with lignocaine in reducing pain on propofol injection. Patients and Methods: 104 patients (ASA...