The purpose of this study was to analyze the effects locking plate fixation used for bridging tibial segmental ostectomy and cast immobilization on gait biomechanics in goats. We hypothesized that stable a bone defect, using construct, would result minimal changes biomechanical variables goats, but full-limb lasting alterations immobilized limb’s kinetics. A pressure-sensing walkway measure cha...

The bones of the vertebrate limb form by the process of endochondral ossification, whereby limb mesenchyme condenses to form an intermediate cartilage scaffold that is then replaced by bone. Although Indian hedgehog (IHH) is known to control hypertophic differentiation of chondrocytes during this process, the role of hedgehog signaling in the earlier stages of chondrogenesis is less clear. We h...

Congenital amputation of a limb is a rare birth defect characterized by failure of formation of the terminal part of an extremity. Also known as congenital transverse deficiency, this condition is thought to be due to mechanical disruption of a developed limb rather than a congenital malformation.1 It can affect one or more limbs2 and an upper limb deformity is more commonly seen.3 We present h...

Poland anomaly was first reported in Guys Hospital report, 1841. Since then many cases have been described. Among the upper limb developmental defects, Poiand anomaly has a prevalence of 1 in 20,000. According to anotherreport 10% of all cases of upper limb syndactyly have Poland anomaly also. Poland anomaly is a sporadic developmental disorder involving the upper limb. Primary defect seems to ...

We describe a 34-year-old male patient with Jacobsen syndrome associated with a broad spectrum of anomalies and an increased susceptibility to infections. Features commonly seen in Jacobsen syndrome were short stature, mental retardation, congenital heart disease, cryptorchidism, strabismus, distal hypospadia glandis, and mild thrombocytopenia. Chromosome analysis disclosed a mosaic 46,XY,del(1...

OBJECTIVES The restoration of an intact covering is the primary surgical requisite following trauma of the lower extremity because deep healing can be no better than the surface covering. The present article is about our experience of lower limb reconstruction using fasciocutaneous flaps. METHODS 20 fasciocutaneous flaps in 15 males and 5 females were used for the wound / defect of lower limb...

VACTERL association is a rare disorder with various congenital malformations. The aetiology remains unknown. Combination of at least three congenital anomalies of the following criteria is required for diagnosis: vertebral defects, anal atresia, cardiac anomalies, tracheo-esophageal fistula, renal anomalies, and limb defects. The first case was 1-day old male neonate with multiple congenital an...

Recent advances in the management of bone tumors have led to a significant increase in the survival rates of patients with malignant bone tumors. Thus, limb salvage surgery has gained importance for preserving limb function in the management of bone tumors. However, surgery presents unique difficulties in terms of the biomechanics and obtaining a soft-tissue cover, such as when the ankle is inv...