Retinoic acid keeps Lingo-1 quiet R etinoic acid (RA) promotes axon regeneration by silencing a key inhibitory receptor, Puttagunta et al. report. Neuronal regrowth after injury is limited, in part, by inhibitory proteins released upon disruption of the surrounding myelin sheath. These proteins bind to the Nogo receptor complex on the neuronal plasma membrane, thereby activating the RhoA GTPase...

Cutting stock problem (CSP) is a of cutting an object into several smaller objects to fulfill the existing demand with minimum unused remaining. Besides minimizing remaining object, sometimes there another additional in CSP, namely number different patterns. This happens because setup cost for each pattern. study shows way obtain patterns (CSP). An example modeled linear programming and then so...

In this paper, we obtain optimum allocation of replaceable and repairable components in a system design. When repair and replace time are considered as random in the constraints. We convert probabilistic constraint into an equivalent deterministic constraint by using chance constrained programming. We have used the selective maintenance policy to determine how many components to be replaced & r...

In this study, we present the problem of shipping a single-product from a single supply origin, through storage depots, to a single demand destination by trucks, ships, etc. and aim to minimize the sum of ordering, inventory and transportation costs over an infinite time horizon. We formulate the problem consisting of power-of-two (PoT ), stationary and nested replenishment policies for the mul...

Many authors have presented studies of multi-choice stochastic transportation problem (MCSTP) where availability and demand parameters follow a particular probability distribution (such as exponential, weibull, cauchy or extreme value). In this paper an MCSTP is considered where availability and demand parameters follow general form of distribution and a generalized equivalent deterministic mod...

Facility location allocation problem is a very important issue in today's global logistic management. Various facility location problems have been considered in operations research under somehow stringent conditions to reduce the search space. In this paper, we consider a class of single source capacitated facility location allocation problems that can assume more realistic conditions in real l...