BACKGROUND: Bony defects arising from tumor resection or debridement after infection, non-union or trauma present a challenging problem to orthopedic surgeons, as well as patients due to compliance issues. Current treatment options are time intensive, require more than one operation and are associated with high rate of complications. For this reason, we developed a new surgical procedure to bri...

Using morselized and structural allograft to restore bone stock for massive acetabular bone defect in revision total hip arthroplasty (THA) is an appealing procedure. However, concerns about inability to achieve long-term stability following allograft resorption remained. From 2003 to 2012, 59 hips in 58 patients undergoing revision THA for Paprosky type II or III acetabular defects were retros...

background: in several conditions we have face cranial bone defects. reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons.   objective: to evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (ocp/bmg).   methods: we used 40, 5–6-week-old male sprague-d...

Revision total hip arthroplasty (THA) with massive bone loss has been a real challenge for orthopaedic surgeons. Here we describe an approach using mineralized collagen (MC) graft to reconstruct acetabulum and femur with massive bone defects. We identified 89 patients suffering acetabular or femoral bone defects after primary THA, who required revision THA for this study. During the surgery, MC...

Bone healing is still a great challenge in orthopedic surgery and clinical practice. There is a dearth of research investigating the effect of Zeolite/Collagen (ZC) nanocomposite on bone regeneration. In the present study, a critical segmental defect of the rabbit femur was repaired using defects in femurs repaired by ZC nanocomposite, and the effects were examined histologically. In total, 45 ...

aneurysms of gastric vessels (dieulafoy`s disease, caliber-persistent artery) are thought to be of malformative rather than degenerative origin. they are usually single, located in the submucosa, usually on the lesser curvature, and characterized by a large tortuous vessel surmounted by a small defect in the overlying mucosa. when the lesion perforates, massive and sometimes fatal hemorrhage ma...

we report 127 cases who have had elective operation on cranium because of skull bone defect during 1984-1989. usually repair of skull bone defect and preserving normal anatomy were the major therapeutic goals. 10, ii in these cases a new surgical technique is described which can successfully accomplish these goals in a single but staged operative procedure.

Objective: In this study, the bone regeneration ability of polyacrylamide hydrogel and nanohydroxyapatite scaffolds (PAAH/NHA) and stem cells derived from adipose tissue (ADSCs) in the healing of critical sized bone defects in rabbit radius were assessed. Animals and procedures: 12 New Zealand white male rabbits were divided into 3 groups. The rabbits were anesthetized and 15 mm bone def...

Reconstruction with massive bone allograft and autologous vascularised fibula combines the structural strength of the allograft and the advantages of fibula's intrinsic blood supply. We retrospectively analysed the outcome of twelve patients (4 male, 8 female) who received reconstruction with massive bone allograft and autologous vascularised fibula after tumour resection in lower limb. Mean ag...