Many of the problems considered in optimization and learning assume that solutions exist in a dynamic. Hence, algorithms are required that dynamically adapt with the problem’s conditions and search new conditions. Mostly, utilization of information from the past allows to quickly adapting changes after. This is the idea underlining the use of memory in this field, what involves key design issue...

There is strong evidence that two cerebral hemispheres are differentially involved in emotional memory and that amygdala is a key subcortical structure for emotional experience. The present research investigated the possible involvement of lateralization of basolateral amygdala (BLA) and central amygdala (CEA) in place avoidance memory. For this purpose, male Long-Evans rats (280-320 g) were im...

Introduction: Learning and memory processes result from interaction of neurotransmitter systems in various brain regions such as amygdala and hippocampus. Considering that morphine induces memory impairment, in the current study, we examined the possible role of cholinergic muscarinic receptors of the central amygdala (CeA) on the morphine-induced amnesia in adult male Wistar rats. Methods...

Verapamil is a drug that blocks L-type calcium channels and selectively inhibits calcium ion entry into the central and peripheral nervous system cells. Verapamil is used acutely and chronically in treatment of some cardiovascular and central nervous system disorders. It has also been shown that acute administration of verapamil has no significant effect on learning and memory in rats, but the ...

Introduction: The current study aimed at investigating the existence of the cross state-dependent learning between morphine and scopolamine (SCO) in mice by passive avoidance method, pointing to the role of CA1 area.  Methods: The effects of pre-training SCO (0.75, 1.5, and 3 μg, Intra-CA1), or morphine (1, 3, and 6 mg/kg, intraperitoneal (i.p.) was evaluated on the retrieval of passiv...

Verapamil is a drug that blocks L-type calcium channels and selectively inhibits calcium ion entry into the central and peripheral nervous system cells. Verapamil is used acutely and chronically in treatment of some cardiovascular and central nervous system disorders. It has also been shown that acute administration of verapamil has no significant effect on learning and memory in rats, but the ...

Introduction: There is currently a debate over the interaction between Ca2+ channels and cannabinoid system on learning and memory processing. In this study, we examined the effect of acute injection of cannabinoid agonist (Win- 55212-2) (Win) or antagonist (AM251), following chronic injection of verapamil, as a L-type Ca2+ channels blocker, on passive avoidance (PA) test in male Wistar rats...