نتایج جستجو برای: methylprednisolone sodium succinate

تعداد نتایج: 198959  

Journal: :Iranian Journal of Veterinary Medicine 2023

Background: Central nervous system (CNS) has limited repair capacity, and any spinal cord injury (SCI) can cause persistent disability in motor, sensory, autonomic functions. The harmful reactions around the lesion must be stopped to prevent this consequence. Objectives: present study compares clinical effects of methylprednisolone sodium succinate (MPSS) meloxicam acute an animal model rats. M...

2017
Michael G. Fehlings Jefferson R. Wilson James S. Harrop Brian K. Kwon Lindsay A. Tetreault Paul M. Arnold Jeffrey M. Singh Gregory Hawryluk Joseph R. Dettori

Study Design Systematic review and meta-analysis. Objective The objective of this study was to conduct a systematic review to assess the comparative effectiveness and safety of high-dose methylprednisolone sodium succinate (MPSS) versus no pharmacological treatment in patients with traumatic spinal cord injury (SCI). Methods A systematic search was performed in PubMed and the Cochrane Colla...

Journal: :Methods in molecular biology 2015
Dongbum Kim Younghee Lee Hyung-Joo Kwon

Antibody production using synthetic peptides has been investigated extensively to develop therapeutic antibodies and prophylactic vaccines. Previously, we reported that a complex of CpG-DNA and synthetic peptides corresponding to B cell epitopes, encapsulated in a phosphatidyl-β-oleoyl-γ-palmitoyl ethanolamine (DOPE):cholesterol hemisuccinate (CHEMS) complex, significantly enhanced the syntheti...

2005
K. M. Fox E. WELMAN J. P. SHILLINGFORD

Serial 72-point precordial mapping of the ECG has been recorded to describe the natural history of changes in the precordial areas of ST segment elevation and the development of Q waves in 51 patients with acute uncomplicated anterior myocardial infarction. Eight patients have been studied in the same way but received 25 mg/kg of methylprednisolone sodium succinate as a single intravenous injec...

Journal: :Infection and immunity 1972
P Wang R C Franson L R DeChatelet M Waite C E McCall

The effect of methylprednisolone sodium succinate treatment on Bacillus Calmette-Guérin (BCG) immunization was examined in alveolar macrophages of New Zealand White rabbits. Intravenous BCG injection caused a marked increase in cell number and in the hexosemonophosphate shunt activity. There was also a selective augmentation in the activity of acid phosphatase and beta-glucuronidase and an incr...

2017
Michael G. Fehlings Jefferson R. Wilson Lindsay A. Tetreault Bizhan Aarabi Paul Anderson Paul M. Arnold Darrel S. Brodke Anthony S. Burns Kazuhiro Chiba Joseph R. Dettori Julio C. Furlan Gregory Hawryluk Langston T. Holly Susan Howley Tara Jeji Sukhvinder Kalsi-Ryan Mark Kotter Shekar Kurpad Brian K. Kwon Ralph J. Marino Allan R. Martin Eric Massicotte Geno Merli James W. Middleton Hiroaki Nakashima Narihito Nagoshi Katherine Palmieri Andrea C. Skelly Anoushka Singh Eve C. Tsai Alexander Vaccaro Albert Yee James S. Harrop

Introduction The objective of this guideline is to outline the appropriate use of methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI). Methods A systematic review of the literature was conducted to address key questions related to the use of MPSS in acute SCI. A multidisciplinary Guideline Development Group used this information, in combination with thei...

Journal: :International journal of clinical and experimental medicine 2015
Xin Li Xiao-Yan Zhang Qiu-Ju Wang Da-Yong Wang

OBJECTIVE To investigate the effect of injecting the methylprednisolone in the ear for the sudden deafness and the improvement of speech discrimination test. METHODS 50 inpatients with a sudden hearing loss were recruited. Inject the methylprednisolone in the subperiosteal of the ear which is 0.5 cm distance to the ear ditch every three days. Methylprednisolone was placed for fifteen days. Si...

2017
Michael G. Fehlings Brian K. Kwon Lindsay A. Tetreault

Study Design Introduction to a guidelines project. Objectives The objective of this focus issue is to present guidelines that outline how to best manage patients with degenerative cervical myelopathy (DCM) and spinal cord injury (SCI). Topics addressed in this focus issue include: 1) management strategies for patients with mild, moderate and severe DCM; and 2a) timing of surgical decompressio...

Journal: :Journal of bacteriology 1990
T A Michel J M Macy

When Selenomonas ruminantium HD4 was grown in a chemostat, maximal succinate production and the highest molar growth yield values were both observed at a dilution rate of roughly 0.2 h-1. To determine the possible relationship between succinate efflux and high molar growth yields, the generation of a membrane potential by succinate efflux was studied in whole cells and vesicles (inside-out and ...

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