Celecoxib, a diaryl substituted pyrazole, is practically insoluble in water which precludes its use in parenteral and liquid dosage forms. This study explores the solubility enhancement of celecoxib using hydrotropy and cosolvency solubilization approaches. The equilibrium solubility studies were performed using hydrotropes piperazine, sodium citrate, and urea and cosolvents PEG 200, PEG 400, P...

The miscibility range for water sodium propionate pentanol mixtures has been determined at 298 K. The phase equilibria are compared with ‘normal’ and ‘ detergentless ’ microemulsion systems. Sodium propionate imposes a very slight salting out action (if any) on pentanol in dilute aqueous solutions. However, pentanol gains full miscibility with concentrated salt solutions. Volumetry was chosen t...

The separation of 2,6 xylidine from 2,4 /2,6 xylidine mixtures in hydrotrope solutions was carried out. The aqueous solubilities of 2,4 xylidine and 2,6 -xylidine in different hydrotropic concentrations (0-3.0 mol/L) of sodium cumene sulfonate , citric acid and nicotinamide solutions at different system temperatures (303 to 333 K ) were studied. The percentage extraction of 2,6xylidine from 2,4...

an experiment was conducted at zahak research station in zabol in 1996-97 to determine the best method of planting and plant density for mixed culture of cucumber and eggplant. in this experiment, yields of two crops were compared in individual and mixed cultures. in both systems the distances between two plant were 25 and 50 cm, and in the mixed culture eggplants were planted in the opposite o...

in the present study, 360 male day-old broiler chicks were used to determine the effect of mixed livevaccines of newcastle disease (nd) and infectious bronchitis (ib) on serum and local antibody responses toib. chicks were randomly divided into 12 treatment groups of 3 replicates and reared for 40 days on floorpens. groups 1 to 5 received mixed nd and ib vaccine. groups 7 to 11 received ib vacc...

laminar mixed convection of aluminium oxide (al2o3)–water nanofluid flow in an inclined annulus using a single-phase approach was numerically studied. constant heat flux boundary conditions were applied on the inner and outer walls. all the thermophysical properties of nanofluid, such as, viscosity, heat capacity, thermal conductivity, and thermal expansion coefficient, except density in the bo...

salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  minor  salivary  gland  tumors (msgts) are uncommon and make up about 10% of all salivary gland neoplasms. the clinical and histopathological distribution of these tumors vary geographically. a case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. the tumor invaded into the anterior surf...