Absrract: We have been concerned with the development of alternate strategies for achievinc; metalion recognition. An important aspect of this research has been to investigate meta! ion complexation over a range of related macrocycles, incorporating different macrocyclic rhg sizes, donor atom set combinations and/or degree of ring substitution and to search for stability rrnxima at different po...

Concerns have been renewed regarding the possible long-term effects of elevated circulating levels of cobalt and chromium as a direct result of implantation of large femoral head diameter metal-on-metal bearings. In order to establish whether metal ion levels remain persistently elevated, we compared metal ion levels before and after revision surgery in patients with large head diameter (greate...

' 'N the accompanying letter by Germer and Haworth, ~ evidence is presented to show that a positive ion in a high field (~107 volts/cm) must be able to eject several electrons from a metal. On the other hand, present theories of ejection by positive ions in low fields require that the ion be neutralized as the first step in the ejection process and, hence, that an ion be unable to eject more th...

a simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon with iminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. the resulting sorbent has been characterized using fourier transform infrared spectroscopy (ft-ir), elemental analysis, thermogravimetric analysis (tga) and evaluated for the preconcentration and de...

Proteins represent the most sophisticated building blocks available to an organism and to the laboratory chemist. Yet, in contrast to nearly all other types of molecular building blocks, the designed self-assembly of proteins has largely been inaccessible because of the chemical and structural heterogeneity of protein surfaces. To circumvent the challenge of programming extensive non-covalent i...

Described is an engineered metal-binding protein, MBPPhen2, which forms porous crystalline frameworks that feature coordinatively unsaturated Zn- and Ni-centers.

Azide ion is an excellent vibrational probe for studying ion-ion and ion-dipole interactions in solutions because its frequency is sensitively dependent on its local environments. When azide ion forms contact ion pairs with cations in dimethylsulfoxide (DMSO), free azide ion and contact ion pairs are spectrally well distinguished in FTIR spectra. Here, we investigated vibrational population rel...

The hammerhead ribozyme is generally accepted as a well characterized metalloenzyme. However, the precise nature of the interactions of the RNA with metal ions remains to be fully defined. Examination of metal ion-catalyzed hammerhead reactions at limited concentrations of metal ions is useful for evaluation of the role of metal ions, as demonstrated in this study. At concentrations of Mn2+ ion...