the density of state and the natural bond orbital calculations were carried out to study theoxidation of co on au14 nano cluster through two different mechanisms and determining the bestmechanism for the reaction. chemisorption of o2 and co on the nano cluster led to change in energy,density of state and its thermodynamic properties. we calculated the energy band gap between thehighest occupied...

Production and approval of trastuzumab (Herceptin®) for the treatment of metastatic breast cancer (MBC) was a millstone in antibody-based targeted therapy in the cancer treatment. However, despite the early success in the clinical trials, trastuzumab failed to appreciate the initial attraction due to development of resistance to the drug. The majority of patients who benefit from the drug...

Background Despite the long history associated with varicocele, it remains one of the most controversial issues in the field of Andrology. The main base of this is our current understanding of the pathophysiology of this disease. This has hampered treatment and management of varicocele, especially regarding why, when and to whom varicocelectomy should be applied. The main molecular pathology of...

imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. interleukin-10(il-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. therefore, alteration in expression of il-10 during pregnancy may result in several pathologic conditions such as preterm labor. il-10 leads to a normal pregna...