BACKGROUND Pancreaticoduodenectomy is associated with a high degree of morbidity; the main cause is failure of the pancreatic anastomosis. It is imperative that this is performed safely and is secure. Pancreatic leaks will lead to serious morbidity and even mortality. Here we describe the use of a new surgical triple-layer pancreaticojejunostomy in a group of patients with minimal morbidity. ...

Five sialic acid variants have been demonstrated in normal, 'transitional', and tumour extracts of human large bowel mucosa by thin-layer chromatography. Two-dimensional thin-layer chromatography, with intermediate alkaline hydrolysis, confirmed that the variants were N-acetyl neuraminic acids with additional O-acylation. Cases studied so far show changes in the proportions of these variants in...

conclusions our data has provided baseline information about epidemiologic aspects of oral mucosal lesions which can be valuable in organized national program targeting on oral health and hygiene in the society. results the prevalence of mucosal lesions in our study was 19.4%. our data demonstrated higher prevalence of oral mucosal lesions in males and young adults (30-40 years). the most commo...

coccidiosis and gizzard erosion are rare conditions in cage bird. a male zebra finch was presented with a history of watery diarrhea, anorexia, ruffled feathers, weight loss, and lethargy and died finally. gross necropsy revealed small areas of erosions and hemorrhages on the gizzard wall. the intestine was oedematous. the spleen appeared pale and small. the testes were asymmetric.histologicall...

Lichen planus (LP) is a chronic inflammatory disease of probable immune-based etiology. The pathogenesis of LP is unclear, but apoptotic changes in epidermal (epithelial) cells have been reported. Destruction of the basal cell layer is observed and many changes in cell proliferation, cell repair and cell death occur in the injured mucosal epithelium. The aim of this study was to evaluate and co...

OBJECTIVE To investigate whether porous titanium can provide a better support for revascularization of a mucosal graft ideal for tracheal reconstruction. In patients with laryngotracheal stenosis or tumor, the mucosa with supporting structures can be damaged, resulting in a defect that has to be reconstructed. Autologous tissues like cartilage and mucosa have been used for reconstruction. The m...

Radiation-induced bladder toxicity is associated with radiation therapy for pelvic malignancies, arising from unavoidable irradiation of neighbouring normal bladder tissue. This study aimed to investigate the acute impact of ionizing radiation on the contractility of bladder strips and identify the radiation-sensitivity of the mucosa vs the detrusor. Guinea-pig bladder strips (intact or mucosa-...

BACKGROUND Ulceration of the oesophageal squamous mucosa (ulcerative oesophagitis) is a pathological manifestation of gastro-oesophageal reflux disease, and is a major risk factor for the development of Barrett's oesophagus. Barrett's oesophagus is characterised by replacement of reflux-damaged oesophageal squamous epithelium with a columnar intestinal-like epithelium. We previously reported di...

The intestine is a long tube, the walls of which are composed of a number of layers: the inner mucosal layer, the function of which is absorption and secretion; a submucosal layer with vascular and lymphatic components in a connective tissue framework forming an important link with the mucosa. Muscle layers follow and form the propulsive mechanism, an inner circular layer which is more powerful...