OBJECTIVES To determine whether acute exercise associated muscle cramping (EAMC) in distance runners is related to changes in serum electrolyte concentrations and hydration status. METHODS A cohort of 72 runners participating in an ultra-distance road race was followed up for the development of EAMC. All subjects were weighed before and immediately after the race. Blood samples were taken bef...

Cramps are sudden, involuntary, painful muscle contractions. Their pathophysiology remains poorly understood. One hypothesis is that cramps result from changes in motor neuron excitability (central origin). Another hypothesis is that they result from spontaneous discharges of the motor nerves (peripheral origin). The central origin hypothesis has been supported by recent experimental findings, ...

clinical assessment of distal symmetric polyneuropathy (dpn) involves the evaluation of symptoms and signs. although there are numerous tools to evaluate dpn, there is still a need to determine the most sensitive, specific, and accurate tests to detect dpn in a busy outpatient clinical setting. a total of 107 patients with type 2 diabetes were examined using michigan neuropathy screening instru...

Mammalian antimicrobial proteins, such as defensins and cathelicidin, have stimulating effects on host leukocytes. Cathelin-related antimicrobial peptide (CRAMP), the orthologue of human cathelicidin/LL-37, is the sole identified murine cathelicidin. CRAMP has been shown to have both antimicrobial and angiogenic activities. However, whether CRAMP, like human cathelicidin/LL-37, also exhibits a ...

BACKGROUND Muscle cramp is a common complication of haemodialysis. The exact mechanism of this complication is still unknown. Many approaches have been used to relieve the muscle cramping but have had variable effects. One of the possible mechanisms of haemodialysis-associated muscle cramps (HAMC) is the disturbance of muscle energy metabolism. Creatine monohydrate can enhance muscle metabolism...

Sensorimotor representations of movements are created in the sensorimotor network through repeated practice to support successful and effortless performance. Writer's cramp (WC) is a disorder acquired through extensive practice of finger movements, and it is likely associated with the abnormal acquisition of sensorimotor representations. We investigated (i) the activation and connectivity chang...

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Introduction: The most common important complications of hemodialysis are hypotension, muscle cramps, nausea and vomiting, which play a significant role in the process dialysis patient’s lifestyle. Objectives: This study aimed to investigate impact serum magnesium on incidence complications. Patients Methods: Two blood samples were obtained from all patients who eligible enter for checking thei...