OBJECTIVES In this study, we investigated the potential harmful effect of the exposure to silicon dioxide (SiO(2)) nanoparticles through in vitro toxicity assay using human bronchial epithelial cell, Beas-2B with a focus on the involvement of oxidative stress as the toxic mechanism. METHODS SiO(2)-induced oxidative stress was assessed by examining formation of reactive oxygen species (ROS), t...

UNLABELLED Matrigel, a mouse sarcoma-derived basement membrane protein mixture, is frequently used to facilitate human tumor xenograft growth in rodents. Despite its known effects on tumor growth and metastasis, its impact on tumor pathophysiology and preclinical evaluation of nanomedicines in tumor xenografts has not been reported previously. Herein bilateral MDA435 tumors were established ort...

Silver nanoparticle therapeutics using symbiotic organisms can offer solutions to the current obstacles in antimicrobial therapies, because of cost-effective and eco-friendly properties over chemical and physical methods. In this study, we aim to synthesize silver nanoparticles using lichen (Parmotrema tinctorum) extract and evaluation of its antibacterial properties. Synthesized silve...

Background: Investigation of toxicity of silver nanoparticle, especxially blood toxicity, is necessary because this nanoparticle is used a lot in diffrerent parts of life and invironment. The aime of this is evaluation the effects of silver nanoparticles with different concentrations on blood cells pregnant Wistar rats. Materials and Methods: In this case control study, 30 pregnant rat wer...

Differential scanning calorimetry and X-ray diffraction play a prominent role in the characterization of lipid nanoparticle (LNP) dispersions. This review shortly outlines the measurement principles of these two techniques and summarizes their applications in the field of nanodispersions of solid lipids. These methods are particularly useful for the characterization of the matrix state, polymor...

There is currently considerable effort to incorporate both diagnostic and therapeutic functions into a single nanoscale system for the more effective treatment of cancer. Nanoparticles have great potential to achieve such dual functions, particularly if more than one type of nanostructure can be incorporated in a nanoassembly, referred to in this review as a hybrid nanoparticle. Here we review ...

We suggest a novel nanoparticle sizing method based on fluorescence polarization analysis. Particle size evaluation can be achieved by measuring the rotational diffusion coefficient, which is sensitive to the particle size. We develop a rotational diffusion coefficient measurement system and a fluorescent probe, which is labelled to particle. In order to verify the feasibility of the proposed m...

Sedimentation analysis of nanoparticle (ZrO(2) and SiO(2)) suspensions of different particle sizes in various solvents as nanoparticle model systems was carried out using interference optics in the analytical ultracentrifuge. The particles differed in their morphology: SiO(2) particles were spherical, whereas ZrO(2) particles were in one case spherical and in the second case non-spherical and s...

Cinnamomum verum-functionalized Fe3O4 nanoparticles of 9.4 nm in size were laser transferred by matrix assisted pulsed laser evaporation (MAPLE) technique onto gastrostomy tubes (G-tubes) for antibacterial activity evaluation toward Gram positive and Gram negative microbial colonization. X-ray diffraction analysis of the nanoparticle powder showed a polycrystalline magnetite structure, whereas ...