A microwave-assisted synthesis of cisplatin, cis-[Pt(NH3)2Cl2], has been developed and optimized on both a 0.2 and 0.05 millimolar scale. The optimized synthetic procedure was modeled after the Lebedinskii-Golovnya method and is suitable for incorporating the radionuclide, (195m)Pt, into cisplatin for biological studies. Highest yields (47%) and purity are obtained using a K2PtCl4 : NH4OAc : KC...

PURPOSE This study describes the development of a rapid and sensitive LC-ESI-MS assay for simultaneous enantioselective determination of levocetirizine and pseudoephedrine in dog plasma in the presence of dextrocetirizine. METHODS Separations were achieved on an Ultron ES-OVM chiral column using the mobile phase consisting of 10 mM aqueous NH4OAc (pH 6.6) and acetonitrile (9:1 v/v). RESULTS...

nonexchangeable soil-k release rate can significantly affect k dynamics and it's bioavailability during plant growth. in this study, twelve soil samples taken from different wheat cropping regions of iran were incubated with nabph4 to (i) investigate the kinetics of nonexchangeable k release and (ii) to compare the ability of various kinetic equations (zero-, first- and second-order, parab...

We report on the fate of nucleic acids conformation in the gas phase as sampled using native mass spectrometry coupled to ion mobility spectrometry. On the basis of several successful reports for proteins and their complexes, the technique has become popular in structural biology, and the conformation survival becomes more and more taken for granted. Surprisingly, we found that DNA and RNA dupl...

A sensitive and selective spectrophotometric method for the determination of boron is described. The method is based on the colour reaction between boron and the reagent 1-(2-hydroxy-3-methoxybenzylideneamino)-8-hydroxynaphthalene-3,6-disulfonic acid (HMOA). In a HOAc-NH4OAc buffer of pH 5.5, HMOA reacts with boron to form a 1:2 yellow complex with a maximum absorption at 423 nm. The absorbance...

Soil Informatics, the GIS-based decision-support system, helps to establish the potentials and limitations of different soils for crop production. A new methodology combining soil survey indices with available nutrients (P and K) was developed to evaluate soil productivity. Physiographic-soil map was generated by interpretation of IRS 1C/1D LISS III satellite data and soil survey in an agricult...

A new method for regiocontrolled pyridine synthesis has been developed involving sequential Rh(I)-catalyzed chelation-assisted hydroacylation of alkynes with aldehydes followed by Rh(III)-promoted N-annulation of the resulting α,β-enones with another alkyne and NH(3).