BACKGROUND Despite the significant role that dyslipidemia is believed to play in the development of cardiovascular disease in diabetes, most studies examining diabetic dyslipidemia in the United States have not been population based, and very little data are available for African Americans with diabetes. We used data from a national survey to compare the effect of diabetes on lipid concentratio...

A bnormalities of coronary microcirculation without large vessel atherosclerosis have been known in patients with non-insulin dependent diabetes mellitus (NIDDM). Coronary flow reserve (CFR) has been considered an important physiological parameter in the coronary circulation reflecting the function of large epicardial arteries and the microcirculation, including endothelial function. Reduced CF...

Our aim was to evaluate oxidative stress in diabetes mellitus by the measurement of biophysical parameters (changes) of hemoglobin macromolecule and some biochemical parameters on two groups of diabetic patients, non-insulin dependent diabetes mellitus (NIDDM), and insulindependent diabetes mellitus (IDDM). This study has been conducted on 45 NIDDM, 30 IDDM, compared to 20 healthy subjects. Blo...

To test the hypothesis that substrate utilization during mild-intensity exercise differs in non-insulin-dependent diabetes mellitus (NIDDM) compared with nondiabetic subjects, seven lean healthy subjects (L), seven obese healthy subjects (O), and seven individuals with NIDDM were studied during 40 min of mild-intensity cycling (40% of peak O2 uptake). Systemic utilization of plasma glucose (Glc...

OBJECTIVE To study the effect of Trichosanthes cucumerina Linn. on non insulin dependent diabetes mellitus induced rats. MATERIALS AND METHODS Non Insulin Dependent Diabetes Mellitus (NIDDM) was induced by administering streptozotocin (90 mg/kg, i.p.) in neonatal rat model. NIDDM animals were treated with aqueous extract of Trichosanthes cucumerina (100 mg/kg/day) orally for six weeks. Parame...

effect of in order to test the memory state in patients with non-insulin dependent diabetes mellitus (niddm) after glycemic control, one-hundred patients referring to isfahan endocrine and metabolism research center were simply randomized. they were compared in point of memory state with one hundred cases as the control group. the wechsler memory scale test was utilized to evaluate the memory s...

Letters to the Editor Microalbuminuria, cardiovas-cular risk factors, and secondary prevention of non-insulin-dependent diabetes Sir, We have read with interest the recent leading article by Drs Dornhorst and Merrin' about the primary, secondary and tertiary prevention of non-insulin-dependent diabetes (NIDDM). Among the possible modes of secondary prevention, the clinical significance of micro...

equal amounts of carbohydrates from various foodstuffs do not increase blood glucose to the same extent. this study was carried out, therefore, in 1996 at the national nutrition and food technology research institute in tehran to determine the glycemic index of split pease, rice (binam), kidney beans, green peas, “lavash” bread and broad bean kernels. diabetic subjects were studied in a clinica...

Insulin resistance is a common feature of non-insulin-dependent diabetes mellitus (NIDDM) and "diabetes susceptibility genes" may be involved in this abnormality. Two potential candidate genes are the insulin receptor (IR) and the insulin-sensitive glucose transporter (GLUT-4). To elucidate whether structural defects in the IR and/or GLUT-4 could be a primary cause of insulin resistance in NIDD...

Recent studies have demonstrated that reduced insulin-stimulated muscle glycogen synthesis is the major cause of insulin resistance in patients with non-insulin-dependent diabetes mellitus (NIDDM). This reduced rate has been assigned to a defect in either glucose transport or hexokinase activity. However it is unknown whether this is a primary or acquired defect in the pathogenesis of NIDDM. To...