Rapid energy-efficient signaling along vertebrate axons is achieved through intricate subcellular arrangements of voltage-gated ion channels and myelination. One recently appreciated example is the tight colocalization of K(v)7 potassium channels and voltage-gated sodium (Na(v)) channels in the axonal initial segment and nodes of Ranvier. The local biophysical properties of these K(v)7 channels...

A procedure is proposed for the automated construction of bending moments influence matrix in frame based on graph its discrete model. Forming incidence characterizing topological structure design scheme frame, through transformations displacement vectors, at transition from local coordinate systems to a global system, it possible establish relationship between nodal displacements and increment...

introduction: the ablation technique is one of the important therapeutic interventions for treatment of av nodal tachyarrhythmia. different animal models have been developed to study the effects of ablation on the functional interanodal structure. the aim of the present study was to develop a new model of computer analysis to produce lesions by using direct voltage in isolated perfused rabbit a...

Introduction: The ablation technique is one of the important therapeutic interventions for treatment of AV Nodal tachyarrhythmia. Different animal models have been developed to study the effects of ablation on the functional interanodal structure. The aim of the present study was to develop a new model of computer analysis to produce lesions by using direct voltage in isolated perfused rabbi...

a lot of researches have investigated the effects of topical cyclosporine a on the eye surface layers' diseases. by now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. the aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. to reach higher corneal dru...

Micropropagation of Vaccinium spp. using Murashige Skoog (MS) and benzylaminopurine (BAP) has been successfully developed. This work aimed to determine the effect different types substrates auxins (naftalen acetic acid NAA, indol IAA y, butyric IBA) on ex vitro establishment rooting nodal segments V. corymbosum Var. Biloxi create a donor bank blueberry plants. The influence five three concentra...

This study explores in detail the functional consequences of subtle retraction and detachment of myelin around the nodes of Ranvier following mild-to-moderate crush or stretch mediated injury. An equivalent electrical circuit model for a series of equally spaced nodes of Ranvier was created incorporating extracellular and axonal resistances, paranodal resistances, nodal capacitances, time varyi...

In competitive electricity markets all over the world, an adoption of suitable transmission pricing model is a problem as transmission segment still operates as a monopoly. Transmission pricing is an important tool to promote investment for various transmission services in order to provide economic, secure and reliable electricity to bulk and retail customers. The nodal pricing based on SRMC (S...

In competitive electricity markets all over the world, an adoption of suitable transmission pricing model is a problem as transmission segment still operates as a monopoly. Transmission pricing is an important tool to promote investment for various transmission services in order to provide economic, secure and reliable electricity to bulk and retail customers. The nodal pricing based on SRMC (S...