Amadeo R. Rodriguez, MD Robert A. Egan, MD Jason J.S. Barton, MD, PhD, FRCPC In skew deviation, one eye is higher than the other, causing vertical diplopia. Skew deviation is a prenuclear disorder resulting from imbalance in otolith input to the oculomotor system, produced by unilateral lesions anywhere from the otoliths to the interstitial nucleus of Cajal in the rostral midbrain,1 and as such...

Ocular bobbing is a distinctive movement disorder occurring in a variety of related forms herein classified as `typical', `monocular', and `atypical'. `Typical' ocular bobbing occurs in patients with paralysis of horizontal conjugate eye movements and consists of abrupt, spontaneous downward jerks of the eyes with a slow return to the mid position. The `monocular' type reflects co-existing unil...

Systemic lupus erythematosus (SLE) is a chronic, immunologic disorder that may affect multiple organ systems. Keratoconjunctivitis sicca is the most common ocular manifestation, but visual morbidity is usually due to retinal and neuro-ophthalmic manifestations of the disease. Ocular manifestations of lupus are a reflection of systemic disease. The presence of ocular manifestations should alert ...

Weill-Marchesani syndrome (WMS) is a rare connective tissue disorder with characteristic phenotypic skeletal and ocular manifestations. A 28-year-old myopic female presented with an 8-month history of bilateral blurred vision. On examination, she was noted to be of short stature with brachydactyly. On ocular examination, she was found to be spherophakic with bilateral inferiorly subluxated lens...

Treacher Collins syndrome is a congenital disorder with bilaterally symmetric anomalies of the structures developing from the first and second branchial arches. The ocular and orbital features are an obligatory component for the diagnosis. We presented a case of typical, complete syndrome and also reviewed the varied ophthalmological manifestations of the disease in the literature. Antimongoloi...

PURPOSE Albinism is a heterogeneous genetic disorder of melanin synthesis that results in hypopigmented eyes (in patients with ocular albinism) or hair, skin, and eyes (in individuals with oculocutaneous albinism). It is associated with decreased visual acuity, nystagmus, strabismus, and photophobia. The tyrosinase gene is known to be involved in both oculocutaneous albinism and autosomal reces...

• Vol 10 • March 2008 Ocular Features of Marfan Syndrome The main ocular features of Marfan syndrome, all of which can result in decreased vision, include bilateral ectopia lentis (lens dislocation), myopia and retinal detachment [1]. About 50% of patients with Marfan syndrome are diagnosed by an ophthalmologist; some individuals may present with isolated ocular signs suggestive of this syndrom...

Epiretinal Membrane (ERM) is characterized by wrinkling or distortion of macular surface caused by glial cell proliferation. It is a common disorder that affects visual acuity, especially in patients older than 50 years. Occasionally, ERM can develop in children and young adults. Epiretinal membranes are generally associated with ocular inflammatory or vascular diseases, tumors, trauma, and ocu...

Sarcoidosis is a systemic multiorgan disorder of unknown etiology characterized by a non-caseating granuloma reaction. Ocular involvement has been reported in 25-60% of the patients. Seven percent of the patients with sarcoidosis may first see an ophthalmologist due to ocular complaints. This report aims to present our diagnostic and treatment approach to a female patient with significant unila...