A series of new synthetic ligand compounds which chelate divalent cations was examined for the antibacterial activities of the compounds. Only 2 of 14 synthetic chelators, 9-trans-anthryl-1, 4, 8, 11-tetraaza-tetradecane (No. 6) and bis(2-pyridyl)methylamine (No. 13) showed antibacterial activities, whereas none of the diamines, hydrophilic triamines nor tetramines showed antibacterial activiti...

A series of water-soluble chiral cyclen-based chelators with chemical handles for selective targeting have been synthesized (cyclen = 1,4,7,10-Tetraazacyclododecane). Optical studies, relaxivity measurements, and competitive titrations were performed to show the versatility these chelators. The complexations L3, L4, L5 Lu3+, Y3+, Sc3+, Cu2+ successfully demonstrated in around 90% 100% yields. E...

The cells of the green unicellular alga Scenedesmus incrassatulus Böhl, strain R-83 released organic chelators for Fe(III) in inorganic nutrient medium both in iron-deficient and in iron-replete conditions. Iron-deficient cells released chelators capable to bind 11nmol Fe. mg (cell DW)–1.h–1, while the chelators released from iron-sufficient cells after contact with Fe(III) were sufficient to b...

objectives: different chelators may be used during root canal treatment, offering various advantages including lubricant effect inside the canal and smear layer removal. however, chelator residues in narrow root canals can lead to apical microleakage. the aim of this in-vitro study was to compare apical microleakage following the use of three root canal chelators via fluid filtration method in ...

Several new analogs of salicylaldehyde isonicotinoyl hydrazone (SIH) and salicylaldehyde benzoyl hydrazone (SBH) that contain an aryl boronic ester (BSIH, BSBH) or acid (BASIH) in place of an aryl hydroxide have been synthesized and characterized as masked metal ion chelators. These pro-chelators show negligible interaction with iron(III), although the boronic acid versions exhibit some interac...

Cystinyl aminopeptidase has one Zn2+-binding motif and is a member of the M1 aminopeptidase family. Ion modulation of its catalytic activity was studied in membranes of CHO-K1 cells (Chinese-hamster ovary K1 cells) using L-leucine-p-nitroanilide as substrate. The planar bidentate chelators 1,10-phenanthroline and 2,2'-bipyridine inhibited the activity in a concentration-dependent manner with Hi...