Human papilloma virus positive (HPV+) tumors represent a large proportion of anal, vulvar, vaginal, cervical and head and neck squamous carcinomas (HNSCC) and late stage invasive disease is thought to originate from a premalignant state. Cyclic dinucleotides that activate STimulator of INterferon Genes (STING) have been shown to cause rapid regression of a range of advanced tumors. We aimed to ...

OBJECT Malignant progression of choroid plexus papillomas has been occasionally reported, but this issue has not yet been systematically addressed. METHODS Frequency and extent of malignant progression were examined in a retrospective series of 124 primary choroid plexus papillomas using uniform histological criteria. RESULTS After gross-total resection and a mean follow-up period of 59 mon...

Inverted papillomas of the nose and paranasal sinuses are uncommon neoplasms, characterized by their tendency to occur and by their association with malignancy. In the past decade there has been a trend toward the use of endoscopic surgical techniques in the management of these tumors. This article presents the results of a prospective study of24 patients with inverted papilloma resected by...

Inverted papillomas are benign but invasive tumors with malignant potential characterized by a high recurrence rate. Although most cases arise from the nasal wall and paranasal sinuses, inverted originating nasolacrimal system have been rarely reported. We describe rare case of an papilloma in left cavity, which originated lacrimal sac 40-year-old female who had medical history endoscopic dacry...

Specific antigen was detected in the bovine cutaneous papil loma by fluorescentlabeled ant iserum prepared against an infectious extract of bovine papilloma. Antigen was present in the nuclei of cells in the keratohyaline and kcratinized layers of the hyperplast ic cpitheliun1 but not in the germinal basal cells. These findings are similar to those reported for the Shope rabbi t papilloma and t...

Verrucous carcinoma (VC) of oral cavity is a rare variant of well-differentiated squamous cell carcinoma and squamous papilloma is a benign proliferation of the stratified squamous epithelium, which results in a papillary or verrucous exophytic mass. There is a certain clinical similarity between squamous cell papilloma and VC. We presented a report of two cases which are VC and squamous cell p...

Specific antigen was detected in the bovine cutaneous papil loma by fluorescentlabeled ant iserum prepared against an infectious extract of bovine papilloma. Antigen was present in the nuclei of cells in the keratohyaline and kcratinized layers of the hyperplast ic cpitheliun1 but not in the germinal basal cells. These findings are similar to those reported for the Shope rabbi t papilloma and t...

Introduction Nasal obstruction is one of the main rhinologic complaints, and two diseases must be investigated as differential diagnosis: rhinosinusal polyposis and inverted papilloma. Using traditional methods, the differential diagnosis between these diseases may be difficult. The morphometric study may be a useful tool for differential diagnosis and to define prognosis. Objective Calculate t...

INTRODUCTION Bronchial papilloma and pulmonary sclerosing hemangioma (PSH) are rare tumors. The development of PSH combined with bronchial papilloma in lung is extremely rare. We herein presented a case of the co-occurrence of bronchial papilloma and PSH in a male. CASE DESCRIPTION A 48-year-old man was referred to our department for further treatment of the productive purulent cough and feve...

choroid plexus papillomas are rare intracranial tumors, accounting for less than 1% of all intracranial tumors in adults. however, they are relatively more common in children and constitute 1.5 to 4% of childhood intracranial tumors. in children, choroid plexus papillomas are predominately located in the lateral ventricles, followed by the forth and third ventricles and, rarely, in the cerebell...