نتایج جستجو برای: permanent cardiac ischemia
تعداد نتایج: 401973 فیلتر نتایج به سال:
Ischemic heart disease (IHD) and diabetes mellitus (DM) are leading causes of death worldwide. Cardiac energy metabolism is profoundly altered in both of these conditions, which can lead to permanent cardiac pathologies that include heart failure and diabetic cardiomyopathy. Diabetic hearts show an increased dependence on oxidation of fatty acids for the production of adenosine triphosphate (AT...
Permanent neurocognitive deficits due to cerebral sequelae account for the majority of longterm morbidity and mortality in survivors of cardiac arrest today. Albeit therapeutic hypothermia had been used as effective measure to ameliorate cerebral ischemia-reperfusion injury during surgery for decades, it was not yet introduced into regular post-arrest care until 2003 due to significant side eff...
BACKGROUND AND PURPOSE Hyperbaric oxygenation (HBO) is an attractive procedure that has been used frequently in cerebral ischemia. However, depending on the model of cerebral ischemia and HBO protocol, different and conflicting results were obtained in the past. This study was undertaken to reevaluate the effects of single administration of HBO in 2 models of acute cerebral ischemia: transient ...
Abstract Background Leptin exerts both protective and deleterious effects on the heart; first occurs under hypoxia- or ischemia-associated damage, second is a pro-hypertrophic factor cardiomyocytes. Therefore, leptin could represent link between obesity cardiovascular diseases. The study aimed to investigate effect of leptin—the same concentration that frequently measured in induces cardiac hyp...
In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...
Objective: The risk of cardiac death in diabetic patients is 3 times more than non-diabetics. But it is not determined who need cardiac screening. About 41% of diabetic patients with silent ischemia are missed. the carotid intima-media thickness (CIMT) and ankel brachial index are two independent,simple and non invasive method in vascular complications diagnosis in diabetic patients.The aim of ...
Previous studies have shown that 1 wk after permanent coronary artery ligation in rats, some cellular mechanisms involving TNF-alpha occur and contribute to the development of cardiac dysfunction and subsequent heart failure. The aim of the present study was to determine whether similar phenomena also occur after ischemia-reperfusion and whether cytokines other than TNF-alpha can also be involv...
conclusions gallic acid and csa combination improved antioxidant capacity and cell membrane integrity more than each one alone. therefore, it can be a therapeutic approach to reduce the i/r injury. background myocardial infarction is one of the important causes of death during old ages. gallic acid as an antioxidant or cyclosporine a (csa) as inhibitor of mitochondrial permeability transition p...
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