background and objectives: pharmaceutical expenditures are responsible for a major part of health systems’ cost. according to the who’s statistics, iran is the first among the 20 countries in the world in terms of drug consumption. the first step in controlling consumption of a particular good is to identify factor inducing the relevant demands. hence, this study aimed to identify the pattern a...

Four best practices help ensure a smooth technology shift to computer modeling and simulation for medical device and pharmaceutical organizations. on living organisms as well as cadavers. This led to tremendous innovation, such as the development of modern surgery, which saved many lives. Later in the 19th century, innovators developed in vitro testing, which was much faster than in vivo experi...

Two-bottle preference tests were done to determine whether pigs detect bitter-tasting compounds. Four standard bitter compounds and nine bitter-tasting pharmaceutical compounds were tested. Pigs detect and avoid taste compounds that humans perceive as bitter-tasting. A dose-response to varying concentrations of bitter tastants can be measured.

In the pharmaceutical industry, a number of tests such as content uniformity and dissolution testing are usually performed at various stages of drug manufacturing process to ensure that the drug product meets standards for identity, strength, quality, purity, and stability of the drug product as specified in the United States Pharmacopedia and National Formulary (USP/NF). The USP/NF provides re...

background: workers exposed to organic solvents are at risk of developing chronic central nervous system disorders. the aim of this cross-sectional study was to investigate the neurobehavioral effects of occupational exposure to organic solvents among pharmaceutical laboratory workers. methods: the study groups consisted of 78 laboratory workers as the exposed group and 98 office workers as une...

OBJECTIVE To compare the pharmaceutical quality of Xenical (chemically produced orlistat) with nine generic products, each produced by fermentation processes. METHODS Xenical 120 mg capsules (Roche, Basel, Switzerland) were used as reference material. Generic products were from India, Malaysia, Argentina, Philippines, Uruguay, and Taiwan. Colour, melting temperature, crystalline form, particl...

b a c k g r o u n d & aim: today, one of the leading causes of pathogenicity and mortality in patients undergoing hemodialysis is their failure to follow the treatment plan. the present research was con- ducted to compare effects of patient-centered  education with family-centered  education on adher- ence with the treatment program. methods & materials: this clinical trial was performed betwee...